Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4A | P47712 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | BACE1 | P56817 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA3 | P07451 | 2/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.47 |
| ▸ | CA4 | P22748 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3608478 | 1.00 | PLA2G4A (0.52) | PLA2G4AMAPTTDP1ATMKDM4E | |
| SCHEMBL3608483 | 1.00 | PLA2G4A (0.52) | PLA2G4AMAPTTDP1ATMKDM4E | |
| SCHEMBL1903142 | 0.88 | PLA2G4A (0.59) | PLA2G4AMAPTTDP1KDM4EKMT2A | |
| SCHEMBL31697463 | 0.88 | PLA2G4A (0.59) | PLA2G4AMAPTTDP1KDM4EKMT2A | |
| SCHEMBL15709537 | 0.88 | PLA2G4A (0.59) | PLA2G4AMAPTTDP1KDM4EKMT2A | |
| SCHEMBL1903144 | 0.88 | PLA2G4A (0.59) | PLA2G4AMAPTTDP1KDM4EKMT2A | |
| SCHEMBL2264118 | 0.83 | KDM4E (0.62) | PLA2G4AMAPTTDP1KDM4EKMT2A | |
| SCHEMBL2264126 | 0.83 | KDM4E (0.62) | PLA2G4AMAPTTDP1KDM4EKMT2A | |
| SCHEMBL30680738 | 0.82 | TTR (0.52) | MAPTTDP1ATMKDM4EKMT2A | |
| SCHEMBL7750518 | 0.82 | TTR (0.52) | MAPTTDP1ATMKDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117177970-A | Polycyclic derivative regulator, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2023-12-05 | — | — | CN | disclosed |
| US-4333940-A | Ring-fluorinated 4-(monosubstituted-amino) phenyl compounds in inhibiting atherosclerotic lesion development | AMERICAN CYANAMID COMPANY (US) | 1982-06-08 | — | — | US | disclosed |
| US-4243609-A | ANTILIPEMIC AGENTS, ANTIATHEROSCLEROTIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1981-01-06 | — | — | US | disclosed |
| EP-0003663-A2 | Amino-substituted phenyl and heteroaryl compounds, process for their preparation and pharmaceutical compositions containing them | AMERICAN CYANAMID COMPANY (US) | 1979-08-22 | — | — | EP | disclosed |