Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
| ▸ | PI4KA | P42356 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2865257 | 0.78 | KMT2A (0.40) | MAPTKMT2APIK3CDPIK3CAPIK3CB | |
| SCHEMBL1892698 | 0.76 | FGFR1 (0.44) | MAPTPIK3CDPIK3CAPIK3CBPI4KA | |
| SCHEMBL14872357 | 0.76 | MAPT (0.35) | MAPTKMT2APIK3CDPIK3CAPIK3CB | |
| SCHEMBL11250319 | 0.72 | — | — | |
| SCHEMBL11266569 | 0.72 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL14639242 | 0.72 | MAPT (0.47) | MAPTKMT2AALDH1A1KDM4ECYP1B1 | |
| SCHEMBL11582604 | 0.68 | — | — | |
| SCHEMBL1687064 | 0.68 | SLC6A2 (0.31) | KMT2A | |
| SCHEMBL9806949 | 0.67 | MAPT (0.43) | MAPTKMT2A | |
| SCHEMBL21392462 | 0.67 | KMT2A (0.52) | MAPTKMT2AKDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4091211-A | ANTIBIOTICS | HOFFMANN-LA ROCHE INC. (US) | 1978-05-23 | — | — | US | claimed |
| US-4348518-A | Cephalosporins | HOFFMANN-LA ROCHE INC. (US) | 1982-09-07 | — | — | US | disclosed |
| US-4091211-A | ANTIBIOTICS | HOFFMANN-LA ROCHE INC. (US) | 1978-05-23 | — | — | US | disclosed |