Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 13/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | CCR2 | P41597 | 1/20 | 0.42 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL861272 | 0.92 | SMN1; SMN2 (0.35) | CXCR4MEN1CHRM2CHRM1ADRA2C | |
| Methane SCHEMBL28950948 | 0.90 | SMN1; SMN2 (0.34) | CXCR4SIGMAR1CHRM5CHRM3 | |
| SCHEMBL11669571 | 0.87 | CXCR4 (0.54) | CXCR4MEN1CHRM2CHRM1ADRA2C | |
| SCHEMBL2204113 | 0.80 | — | — | |
| SCHEMBL9308707 | 0.80 | — | — | |
| SCHEMBL64922 | 0.79 | CXCR4 (0.50) | CXCR4MEN1CHRM2CHRM1ADRA2C | |
| SCHEMBL8757759 | 0.79 | CXCR4 (0.50) | CXCR4MEN1CHRM2CHRM1ADRA2C | |
| SCHEMBL10529827 | 0.79 | — | — | |
| SCHEMBL861622 | 0.78 | CHRNB2 (0.39) | MEN1KMT2AHRH3SIGMAR1 | |
| Hydrochloric Acid SCHEMBL11868810 | 0.76 | CHRNB2 (0.38) | MEN1KMT2AHRH3SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57200370-A | — | — | None | — | — | JP | disclosed |
| JP-S57200370-A | 1-ACYL GROUP SUBSTITUTED-4-HYDROXYALKYLHOMOPIPERAZINE DERIVATIVE | HOKURIKU SEIYAKU CO LTD | 1982-12-08 | — | — | JP | disclosed |