Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.56 |
| ▸ | LDHA | P00338 | 1/20 | 0.53 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.53 |
| ▸ | EGFR | P00533 | 4/20 | 0.52 |
| ▸ | NR2F2 | P24468 | 3/20 | 0.52 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | GALR3 | O60755 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11246726 | 0.88 | LDHA (0.50) | APPLDHAKCNA5EGFRNR2F2 | |
| SCHEMBL11251106 | 0.86 | LDHA (0.49) | APPLDHAKCNA5EGFRNR2F2 | |
| SCHEMBL11245793 | 0.83 | EGFR (0.54) | APPLDHAEGFRNR2F2ABCG2 | |
| SCHEMBL11250104 | 0.80 | EGFR (0.52) | APPLDHAEGFRNR2F2POLB | |
| SCHEMBL11256393 | 0.79 | LDHA (0.55) | APPLDHAEGFRNR2F2POLB | |
| SCHEMBL11104495 | 0.79 | KCNA5 (0.44) | APPKCNA5EGFRMAPK1CYP1A2 | |
| SCHEMBL11242446 | 0.79 | EGFR (0.57) | APPLDHAEGFRNR2F2POLB | |
| SCHEMBL11260502 | 0.79 | EGFR (0.51) | APPLDHAEGFRNR2F2ABCG2 | |
| SCHEMBL11262398 | 0.78 | LDHA (0.72) | APPLDHAEGFRNR2F2ABCG2 | |
| SCHEMBL11248676 | 0.77 | EGFR (0.52) | APPLDHAEGFRNR2F2ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4323680-A | 4-Aminoquinazoline compounds useful as agricultural fungicides | SANKYO COMPANY LIMITED (JP) | 1982-04-06 | — | — | US | disclosed |
| US-4213987-A | 4-AMINOQUINAZOLINES | SANKYO COMPANY LIMITED (JP) | 1980-07-22 | — | — | US | disclosed |