Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SKP2 | Q13309 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.37 |
| ▸ | LPL | P06858 | 2/20 | 0.36 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11467020 | 0.88 | SKP2 (0.65) | SKP2RAB9ANPC1CA2TP53 | |
| SCHEMBL23007565 | 0.86 | SKP2 (0.58) | SKP2RAB9AMAPTCA2TP53 | |
| SCHEMBL8553254 | 0.86 | SKP2 (0.62) | SKP2RAB9ANPC1CA2TP53 | |
| SCHEMBL5946730 | 0.85 | SKP2 (0.56) | SKP2RAB9AMAPTTP53SMN1; SMN2 | |
| SCHEMBL11137866 | 0.85 | SKP2 (0.56) | SKP2RAB9AMAPTTP53SMN1; SMN2 | |
| SCHEMBL11323114 | 0.85 | SKP2 (0.56) | SKP2RAB9AMAPTTP53SMN1; SMN2 | |
| SCHEMBL8499826 | 0.83 | SKP2 (0.54) | SKP2RAB9AMAPTTP53SMN1; SMN2 | |
| SCHEMBL8417108 | 0.83 | SKP2 (0.54) | SKP2RAB9AMAPTTP53SMN1; SMN2 | |
| SCHEMBL11825352 | 0.83 | SKP2 (0.44) | SKP2CNR1CNR2RAB9ANPC1 | |
| SCHEMBL11308617 | 0.83 | NOS3 (0.42) | SKP2RAB9ANPC1MAPTCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9957241-B2 | Aromatic diamine, an intermediate therefor, a method for producing the aromatic diamine, and a method for producing the intermediate therefor | SEIKA CORPORATION (JP) | 2018-05-01 | — | — | US | disclosed |
| US-20180079732-A1 | AROMATIC DIAMINE, AN INTERMEDIATE THEREFOR, A METHOD FOR PRODUCING THE AROMATIC DIAMINE, AND A METHOD FOR PRODUCING THE INTERMEDIATE THEREFOR | SEIKA CORPORATION (JP) | 2018-03-22 | — | — | US | disclosed |
| EP-2738208-B1 | COUPLING AGENT FOR RUBBER/CARBON BLACK, AND RUBBER COMPOSITION CONTAINING SAME FOR USE IN TIRES | SHIKOKU CHEM (JP) | 2017-07-19 | — | — | EP | disclosed |
| US-9200145-B2 | Coupling agent for rubber/carbon black, and rubber composition containing same for use in tires | SHIKOKU CHEMICALS CORPORATION (JP) | 2015-12-01 | — | — | US | disclosed |
| US-20140155541-A1 | COUPLING AGENT FOR RUBBER/CARBON BLACK, AND RUBBER COMPOSITION CONTAINING SAME FOR USE IN TIRES | SHIKOKU CHEMICALS CORPORATION (JP) | 2014-06-05 | — | — | US | disclosed |
| EP-2738208-A1 | COUPLING AGENT FOR RUBBER/CARBON BLACK, AND RUBBER COMPOSITION CONTAINING SAME FOR USE IN TIRES | Shikoku Chemicals Corporation (JP) | 2014-06-04 | — | — | EP | disclosed |
| CN-1474844-A | Polybenzole compound having sulfo group and/or phosphono group, resin composition containing same, molded resin, solid polymer electrotyte film, solid electrolyte film/electrode catalyst layer ... | �����֯��ʽ���� | 2004-02-11 | — | — | CN | disclosed |
| US-4321393-A | Method for preparing 2-cyanamidobenzimidazoles or 2-cyanamidobenzoxazoles | SMITHKLINE CORPORATION (US) | 1982-03-23 | — | — | US | disclosed |
| US-4285878-A | N-Phenyl-N'-cyano-O-phenylisoureas | SMITHKLINE CORPORATION (US) | 1981-08-25 | — | — | US | disclosed |
| US-3984405-A | PYRIDO(3,2-B)(1,4)OXAZIN-3(4H)-ONES | E. R. SQUIBB & SONS, INC. (US) | 1976-10-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180079732-A1 | AROMATIC DIAMINE, AN INTERMEDIATE THEREFOR, A METHOD FOR PRODUCING THE AROMATIC DIAMINE, AND A METHOD FOR PRODUCING THE INTERMEDIATE THEREFOR | WEE1, WEE2, WASF2 | SKP2 1026/4885CNR1 3668/4885CNR2 2573/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.