Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | CDK1 | P06493 | 2/20 | 0.53 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.53 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.53 |
| ▸ | CDK2 | P24941 | 2/20 | 0.53 |
| ▸ | HBB | P68871 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.47 |
| ▸ | PNP | P00491 | 5/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | EDNRA | P25101 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | NT5E | P21589 | 1/20 | 0.43 |
| ▸ | HPRT1 | P00492 | 3/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9366819 | 0.89 | MEN1 (0.56) | MEN1KMT2ATSHRHBBMAPK1 | |
| SCHEMBL9426463 | 0.84 | ENPP1 (0.61) | MEN1KMT2ATSHRENPP1NT5E | |
| SCHEMBL19553462 | 0.83 | CDK1 (0.53) | MEN1KMT2ATSHRCDK1CCNB1 | |
| SCHEMBL11249255 | 0.83 | EGFR (0.46) | MEN1KMT2ATSHRCDK1CCNB1 | |
| SCHEMBL11724984 | 0.82 | PNP (0.60) | MEN1KMT2ATSHRCDK1CCNB1 | |
| SCHEMBL571583 | 0.82 | PNP (0.62) | MEN1KMT2ATSHRCDK1CCNB1 | |
| SCHEMBL9583183 | 0.81 | CCNE1 (0.51) | MEN1KMT2ATSHRCDK1CCNB1 | |
| Hydrochloric Acid SCHEMBL11250267 | 0.81 | PNP (0.61) | MEN1KMT2ATSHRCDK1CCNB1 | |
| SCHEMBL8926305 | 0.81 | HSD17B10 (0.61) | MEN1KMT2ATSHRHBBMAPK1 | |
| SCHEMBL5053218 | 0.80 | MEN1 (0.57) | MEN1KMT2ATSHRHBBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4360522-A | VIRICIDES | BURROUGHS WELLCOME CO. (US) | 1982-11-23 | — | — | US | disclosed |
| US-4323573-A | VIRICIDES | BURROUGHS WELLCOME CO. (US) | 1982-04-06 | — | — | US | disclosed |
| US-4294831-A | ANTIVIRAL ACTIVITY | BURROUGHS WELLCOME CO. (US) | 1981-10-13 | — | — | US | disclosed |
| US-4287188-A | PARTICULARLY 9-(2-HYDROXYETHOXYMETHYL) GUANINE MONOPHOSPHATE AND SALTS, USEFUL AS ANTIVIRIAL AGENTS | BURROUGHS WELLCOME CO. (US) | 1981-09-01 | — | — | US | disclosed |
| US-4199574-A | Methods and compositions for treating viral infections and guanine acyclic nucleosides | BURROUGHS WELLCOME CO. (US) | 1980-04-22 | — | — | US | disclosed |
| US-4146715-A | ANTIVIRAL AGENTS | BURROUGHS WELLCOME CO. (US) | 1979-03-27 | — | — | US | disclosed |