Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.61 |
| ▸ | NPC1 | O15118 | 5/20 | 0.57 |
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | RAB9A | P51151 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 6/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.44 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10613167 | 0.81 | NPC1 (0.83) | TSHRNPC1MAPTRAB9AALDH1A1 | |
| SCHEMBL19707225 | 0.79 | TSHR (0.59) | TSHRNPC1MAPTRAB9AALDH1A1 | |
| SCHEMBL19707227 | 0.79 | TSHR (0.70) | TSHRNPC1MAPTRAB9AALDH1A1 | |
| SCHEMBL4359332 | 0.78 | MEN1 (0.56) | TSHRNPC1MAPTRAB9AALDH1A1 | |
| Monuron SCHEMBL8539289 | 0.76 | TSHR (1.00) | TSHRNPC1RAB9AALDH1A1PKM | |
| Monuron SCHEMBL106717 | 0.76 | TSHR (1.00) | TSHRNPC1RAB9AALDH1A1PKM | |
| Monuron SCHEMBL9370512 | 0.76 | TSHR (1.00) | TSHRNPC1RAB9AALDH1A1PKM | |
| SCHEMBL10434328 | 0.75 | TSHR (0.54) | TSHRNPC1MAPTRAB9AALDH1A1 | |
| SCHEMBL11860609 | 0.74 | TSHR (0.75) | TSHRNPC1MAPTRAB9AALDH1A1 | |
| SCHEMBL9871496 | 0.74 | RAB9A (0.63) | TSHRNPC1MAPTRAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4357476-A | Nonylamines | CIBA GEIGY CORPORATION, N.Y. (US) | 1982-11-02 | — | — | US | disclosed |
| US-4336270-A | BACTERICIDES, FUNGICIDES | CIBA-GEIGY CORPORATION (US) | 1982-06-22 | — | — | US | disclosed |
| US-4160833-A | ANIMAL FEED ADDITIVE AND MICROBIOCIDE | CIBA-GEIGY CORPORATION (US) | 1979-07-10 | — | — | US | disclosed |
| US-4139560-A | Nonylamines | CIBA GEIGY CORPORATION (US) | 1979-02-13 | — | — | US | disclosed |
| US-3991124-A | FOR CONTROLLING MICROORGANISMS AND HELMINTHS | CIBA-GEIGY CORPORATION (US) | 1976-11-09 | — | — | US | disclosed |
| US-3956402-A | MICROBIOCIDES | CIBA-GEIGY CORPORATION (US) | 1976-05-11 | — | — | US | disclosed |