Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.40 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3051191 | 0.84 | ALDH1A1 (0.64) | ALDH1A1TP53CYP3A4SMN1; SMN2LMNA | |
| SCHEMBL27469055 | 0.82 | ALDH1A1 (0.61) | ALDH1A1TP53CYP3A4SMN1; SMN2LMNA | |
| SCHEMBL11483970 | 0.82 | ALDH1A1 (0.61) | ALDH1A1TP53CYP3A4SMN1; SMN2LMNA | |
| SCHEMBL28430294 | 0.80 | SMN1; SMN2 (0.56) | ALDH1A1TP53CYP3A4SMN1; SMN2LMNA | |
| Cyclohexylamine SCHEMBL11174371 | 0.75 | ALDH1A1 (0.52) | ALDH1A1TP53CYP3A4SMN1; SMN2LMNA | |
| SCHEMBL8137671 | 0.73 | ALDH1A1 (0.60) | KMT2AALDH1A1EPHX1KDM4E | |
| SCHEMBL11529346 | 0.73 | HTT (0.53) | KMT2AALDH1A1TP53CYP3A4PKM | |
| SCHEMBL5543349 | 0.72 | SMN1; SMN2 (0.50) | ALDH1A1TP53CYP3A4SMN1; SMN2LMNA | |
| Cyclopentane SCHEMBL9838016 | 0.71 | ALDH1A1 (0.44) | ALDH1A1MAPK1HTT | |
| SCHEMBL38660588 | 0.70 | KMT2A (0.57) | KMT2AALDH1A1SMN1; SMN2LMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4341707-A | CHEMICAL INTERMEDIATES; PEPTIDE SYNTHESIS | Ogura, Haruo (JP) | 1982-07-27 | — | — | US | disclosed |