Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMOX1 | P09601 | 3/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | MTOR | P42345 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | GMNN | O75496 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11246856 | 0.95 | HMOX1 (0.53) | HMOX1TP53CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11233202 | 0.90 | TP53 (0.49) | HMOX1TP53CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11246299 | 0.89 | HMOX1 (0.72) | HMOX1 | |
| SCHEMBL11246746 | 0.89 | MEN1 (0.50) | HMOX1TP53CYP1A2CYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL11245468 | 0.88 | HMOX1 (0.73) | HMOX1 | |
| SCHEMBL11238453 | 0.88 | TP53 (0.45) | HMOX1TP53CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11246238 | 0.87 | HMOX1 (0.61) | HMOX1 | |
| SCHEMBL11242859 | 0.85 | HMOX1 (0.66) | HMOX1 | |
| SCHEMBL11247617 | 0.85 | MEN1 (0.48) | HMOX1TP53CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11239197 | 0.85 | HMOX1 (0.65) | HMOX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0049565-A2 | Derivatives of substituted N-alkylimidazoles, their preparation and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1982-04-14 | — | — | EP | disclosed |
| US-4321272-A | Derivatives of substituted N-alkylimidazoles | SYNTEX (U.S.A.) INC. (US) | 1982-03-23 | — | — | US | disclosed |