Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 4/20 | 0.53 |
| ▸ | MAOB | P27338 | 4/20 | 0.53 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | PTGIR | P43119 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.33 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27357404 | 0.84 | MAOA (0.49) | MAOAMAOBARPTGIRSMN1; SMN2 | |
| SCHEMBL18702813 | 0.81 | MAOA (0.48) | MAOAMAOBARPTGIRMEN1 | |
| SCHEMBL29503064 | 0.81 | MAOA (0.48) | MAOAMAOBARPTGIRMEN1 | |
| SCHEMBL12218337 | 0.78 | MAOA (0.58) | MAOAMAOBARPTGIRSMN1; SMN2 | |
| SCHEMBL26000309 | 0.78 | MAOA (0.58) | MAOAMAOBARPTGIRSMN1; SMN2 | |
| SCHEMBL2656706 | 0.78 | MAOA (0.73) | MAOAMAOBARMEN1KMT2A | |
| SCHEMBL5625530 | 0.76 | MAOA (0.43) | MAOAMAOBARCA2CA12 | |
| SCHEMBL23295277 | 0.76 | MAOA (0.65) | MAOAMAOBARPTGIRSMN1; SMN2 | |
| SCHEMBL19890876 | 0.75 | MAOA (0.55) | MAOAMAOBARPTGIRMEN1 | |
| SCHEMBL22288286 | 0.73 | MAOA (0.53) | MAOAMAOBARPTGIRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4321393-A | Method for preparing 2-cyanamidobenzimidazoles or 2-cyanamidobenzoxazoles | SMITHKLINE CORPORATION (US) | 1982-03-23 | — | — | US | disclosed |
| US-4285878-A | N-Phenyl-N'-cyano-O-phenylisoureas | SMITHKLINE CORPORATION (US) | 1981-08-25 | — | — | US | disclosed |