Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | VCAM1 | P19320 | 7/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11330182 | 0.85 | TDP1 (0.52) | TDP1TSHRSMN1; SMN2MAPK1CYP3A4 | |
| SCHEMBL4864448 | 0.82 | TDP1 (0.57) | TDP1TSHRSMN1; SMN2MAPK1CYP3A4 | |
| SCHEMBL899707 | 0.81 | TDP1 (0.52) | TDP1TSHRSMN1; SMN2MAPK1CYP3A4 | |
| SCHEMBL30256667 | 0.80 | TDP1 (0.67) | TDP1TSHRSMN1; SMN2MAPK1CYP3A4 | |
| SCHEMBL278506 | 0.80 | TDP1 (0.67) | TDP1TSHRSMN1; SMN2MAPK1CYP3A4 | |
| SCHEMBL2002527 | 0.78 | TDP1 (0.53) | TDP1TSHRSMN1; SMN2MAPK1CYP3A4 | |
| SCHEMBL11594677 | 0.77 | TSHR (0.52) | TDP1TSHRSMN1; SMN2CYP3A4MAPT | |
| SCHEMBL27917309 | 0.77 | TDP1 (0.52) | TDP1TSHRSMN1; SMN2MAPK1CYP3A4 | |
| SCHEMBL11040922 | 0.77 | TDP1 (0.52) | TDP1TSHRSMN1; SMN2MAPK1CYP3A4 | |
| SCHEMBL27751205 | 0.77 | TDP1 (0.52) | TDP1TSHRSMN1; SMN2MAPK1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4349377-A | Phenoxyphenylthioalkanecarboxylic acid amides and their use as herbicides and plant growth regulants | CIBA-GEIGY CORPORATION (US) | 1982-09-14 | — | — | US | disclosed |
| EP-0000359-B1 | PHENOXY-PHENYLSULFINYL-AND-SULFONYLALKANECARBOXYLIC ACID DERIVATIVES, METHOD FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES AND PLANT GROWTH REGULATORS. | CIBA-GEIGY AG (CH) | 1981-10-21 | — | — | EP | disclosed |
| EP-0000351-A1 | Phenoxy-phenyl-thio-alkanecarboxylic acid derivatives method for their preparation and their use as herbicides and plant growth regulators | CIBA-GEIGY AG (CH) | 1979-01-24 | — | — | EP | disclosed |