Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPG | P10696 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11250680 | 1.00 | ALPG (0.42) | ALPGAKR1B1GRIN1GRIN2AKDM4E | |
| SCHEMBL11263149 | 0.88 | ALPG (0.44) | ALPGAKR1B1GRIN1GRIN2AKDM4E | |
| SCHEMBL11245711 | 0.88 | ALPG (0.42) | ALPGAKR1B1GRIN1GRIN2AKDM4E | |
| SCHEMBL11245712 | 0.88 | ALPG (0.42) | ALPGAKR1B1GRIN1GRIN2AKDM4E | |
| SCHEMBL11263153 | 0.88 | ALPG (0.44) | ALPGAKR1B1GRIN1GRIN2AKDM4E | |
| SCHEMBL11257063 | 0.86 | CDK4 (0.40) | ALPGAKR1B1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL11257070 | 0.86 | CDK4 (0.40) | ALPGAKR1B1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL11263960 | 0.86 | ALPG (0.47) | ALPGKDM4EALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL11263955 | 0.86 | ALPG (0.47) | ALPGKDM4EALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL11258061 | 0.84 | AKR1B1 (0.43) | ALPGAKR1B1KDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4341780-A | Substituted pyrido [1,2-a] pyrimidines useful as anti-allergic, anti-ulcer and anti-diabetic agents | FARMITALIA CARLO ERBA S.P.A. (IT) | 1982-07-27 | — | — | US | disclosed |
| US-4310526-A | Substituted 6,7-methylene pyrido[1,2-a]pyrimidines useful as anti-allergic and anti-ulcer agents | FARMITALIA CARLO ERBA S.P.A. (IT) | 1982-01-12 | — | — | US | disclosed |