Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | PKM | P14618 | 2/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.48 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.48 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11545988 | 0.87 | HPGD (0.57) | HPGDMEN1KMT2APKMTHRB | |
| SCHEMBL14427603 | 0.85 | MEN1 (0.66) | HPGDMEN1KMT2AHTTALDH1A1 | |
| SCHEMBL18773872 | 0.82 | HPGD (0.64) | HPGDMEN1KMT2APKMTHRB | |
| SCHEMBL15676769 | 0.81 | KMT2A (0.58) | HPGDMEN1KMT2AHTTALDH1A1 | |
| SCHEMBL1006444 | 0.80 | HTT (0.71) | HPGDMEN1KMT2AHTTALDH1A1 | |
| SCHEMBL7987353 | 0.80 | MEN1 (0.59) | HPGDMEN1KMT2AHTTALDH1A1 | |
| SCHEMBL1196964 | 0.78 | KMT2A (0.58) | HPGDMEN1KMT2AHTTALDH1A1 | |
| SCHEMBL28284716 | 0.77 | MEN1 (0.51) | MEN1KMT2AHTTALDH1A1SMN1; SMN2 | |
| SCHEMBL10268483 | 0.77 | KMT2A (0.57) | HPGDMEN1KMT2AHTTALDH1A1 | |
| SCHEMBL3454665 | 0.77 | MEN1 (0.76) | HPGDMEN1KMT2AHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0022750-B1 | 1,3,4-THIADIAZOLYLOXY-PHENYL UREAS, THEIR PREPARATION AND HERBICIDES CONTAINING THEM | CIBA-GEIGY AG (CH) | 1983-05-18 | — | — | EP | disclosed |