Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA6 | P23280 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14427603 | 0.90 | MEN1 (0.66) | MEN1KMT2AHTTALDH1A1TSHR | |
| SCHEMBL1006444 | 0.85 | HTT (0.71) | MEN1KMT2AHTTALDH1A1TSHR | |
| SCHEMBL11503382 | 0.84 | ADRA2C (0.49) | MEN1KMT2AHTTALDH1A1TSHR | |
| SCHEMBL18773872 | 0.84 | HPGD (0.64) | MEN1KMT2AHTTALDH1A1TSHR | |
| SCHEMBL1196964 | 0.83 | KMT2A (0.58) | MEN1KMT2AHTTALDH1A1TSHR | |
| SCHEMBL15676769 | 0.83 | KMT2A (0.58) | MEN1KMT2AHTTALDH1A1TSHR | |
| SCHEMBL10268483 | 0.82 | KMT2A (0.57) | MEN1KMT2AHTTALDH1A1TSHR | |
| SCHEMBL6430222 | 0.81 | MEN1 (0.63) | MEN1KMT2AHTTALDH1A1TSHR | |
| SCHEMBL11250720 | 0.80 | HPGD (0.59) | MEN1KMT2AHTTALDH1A1TSHR | |
| SCHEMBL7927019 | 0.79 | MEN1 (0.48) | MEN1KMT2AALDH1A1TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6297239-B1 | Inhibitors of prenyl-protein transferase | MERCK & CO., INC. | 2001-10-02 | — | — | US | disclosed |