Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | PGR | P06401 | 1/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | HRH1 | P35367 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27715083 | 0.89 | NPC1 (0.59) | MEN1KMT2ANPC1PGRADRA2A | |
| SCHEMBL16050447 | 0.88 | MEN1 (0.54) | MEN1KMT2ANPC1PGRADRA2A | |
| SCHEMBL5866532 | 0.84 | KMT2A (0.57) | MEN1KMT2ANPC1PGRADRA2A | |
| SCHEMBL1156167 | 0.83 | KMT2A (0.50) | MEN1KMT2ANPC1PGRADRA2A | |
| SCHEMBL8834224 | 0.83 | MEN1 (0.53) | MEN1KMT2ANPC1PGRADRA2A | |
| SCHEMBL4924103 | 0.83 | NPC1 (0.53) | MEN1KMT2ANPC1PGRADRA2A | |
| SCHEMBL5106630 | 0.83 | MEN1 (0.53) | MEN1KMT2ANPC1PGRADRA2A | |
| SCHEMBL396482 | 0.82 | MEN1 (0.56) | MEN1KMT2ANPC1PGRADRA2A | |
| SCHEMBL2098734 | 0.81 | NPC1 (0.59) | MEN1KMT2ANPC1PGRADRA2A | |
| SCHEMBL28226195 | 0.81 | NPC1 (0.59) | MEN1KMT2ANPC1PGRADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4325962-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, ANTIDYRETICS | BYK-GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1982-04-20 | — | — | US | disclosed |
| US-4146721-A | ANALGESICS, ANTIINFLAMMATORY AGENTS AND ANTIPYRETICS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1979-03-27 | — | — | US | disclosed |