Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.75 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.75 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | ACHE | P22303 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Styrene SCHEMBL7641096 | 0.89 | TP53 (0.87) | TP53TDP1TSHRALDH1A1ACHE | |
| Benzene SCHEMBL28405057 | 0.88 | TP53 (0.95) | TP53TDP1TSHRALDH1A1ACHE | |
| Styrene SCHEMBL271801 | 0.88 | ALDH1A1 (0.74) | TP53TDP1TSHRALDH1A1ACHE | |
| Styrene SCHEMBL8859296 | 0.88 | ALDH1A1 (0.74) | TP53TDP1TSHRALDH1A1ACHE | |
| Styrene SCHEMBL6061931 | 0.86 | TP53 (0.75) | TP53TDP1TSHRALDH1A1ACHE | |
| Styrene SCHEMBL6152918 | 0.86 | ALDH1A1 (0.70) | TP53TDP1TSHRALDH1A1ACHE | |
| SCHEMBL679453 | 0.86 | TP53 (1.00) | TP53TDP1TSHRALDH1A1ACHE | |
| SCHEMBL15008 | 0.86 | — | — | |
| SCHEMBL29464940 | 0.86 | — | — | |
| Styrene SCHEMBL8164745 | 0.86 | ALDH1A1 (0.70) | TP53TDP1TSHRALDH1A1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4311799-A | DIVINYLBENZENE, AMINOETHYLSTYRENE DERIVATIVE | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1982-01-19 | — | — | US | disclosed |