Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 8/20 | 0.33 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.32 |
| ▸ | TOP2A | P11388 | 1/20 | 0.31 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.30 |
| ▸ | RELA | Q04206 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.30 |
| ▸ | METAP1 | P53582 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9122699 | 0.87 | CA1 (0.40) | CA1CA2LCKPSMB8NPC1 | |
| SCHEMBL9122704 | 0.87 | CA1 (0.40) | CA1CA2LCKPSMB8NPC1 | |
| SCHEMBL11259482 | 0.85 | CA1 (0.38) | CA1CA2LCKPSMB8 | |
| SCHEMBL8761670 | 0.84 | CA1 (0.41) | CA1CA2LCKPSMB8NPC1 | |
| SCHEMBL8761680 | 0.84 | CA1 (0.41) | CA1CA2LCKPSMB8NPC1 | |
| SCHEMBL15519217 | 0.83 | CA1 (0.37) | CA1CA2LCKPSMB8NPC1 | |
| SCHEMBL5148637 | 0.83 | CA1 (0.39) | CA1CA2LCKPSMB8NPC1 | |
| SCHEMBL5148633 | 0.83 | CA1 (0.39) | CA1CA2LCKPSMB8NPC1 | |
| SCHEMBL9122512 | 0.83 | CA1 (0.37) | CA1CA2LCKPSMB8NPC1 | |
| SCHEMBL9122518 | 0.83 | CA1 (0.37) | CA1CA2LCKPSMB8NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0047977-A2 | Cephalosporin derivatives, process for their preparation, pharmaceutical compositions containing them and their use | CIBA-GEIGY AG (CH) | 1982-03-24 | — | — | EP | disclosed |
| EP-0025017-A1 | Polyazathia compounds, process for their preparation, pharmaceutical preparations containing such compounds and use of the latter | CIBA-GEIGY AG (CH) | 1981-03-11 | — | — | EP | disclosed |