SCHEMBL11259482

SCHEMBL11259482

CNC(=O)/N=C(\C(=O)O)c1nsc(NC(=O)OC(C)(C)C)n1

nearest known ligand 0.38

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
LCK P06239 13/20 0.35
PSMB8 P28062 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8761670 0.85 CA1 (0.41) CA1CA2LCKPSMB8
SCHEMBL8761680 0.85 CA1 (0.41) CA1CA2LCKPSMB8
SCHEMBL11253247 0.85 CA1 (0.38) CA1CA2LCKPSMB8
SCHEMBL9122704 0.83 CA1 (0.40) CA1CA2LCKPSMB8
SCHEMBL9122699 0.83 CA1 (0.40) CA1CA2LCKPSMB8
SCHEMBL10669772 0.80 CA1 (0.36) CA1CA2LCKPSMB8
SCHEMBL10669764 0.80 CA1 (0.36) CA1CA2LCKPSMB8
SCHEMBL9121665 0.79 CA1 (0.45) CA1CA2LCKPSMB8
SCHEMBL31337188 0.79 CA1 (0.50) CA1CA2LCKPSMB8
SCHEMBL5148637 0.79 CA1 (0.39) CA1CA2LCKPSMB8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0047977-A2 Cephalosporin derivatives, process for their preparation, pharmaceutical compositions containing them and their use CIBA-GEIGY AG (CH) 1982-03-24 EP disclosed