Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 6/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 6/20 | 0.58 |
| ▸ | NPC1 | O15118 | 5/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | NAMPT | P43490 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11240962 | 0.85 | MAPT (0.59) | TRPV1MAPTALDH1A1LMNAKMT2A | |
| SCHEMBL11238983 | 0.84 | MAPT (0.71) | TRPV1MAPTALDH1A1LMNAKMT2A | |
| SCHEMBL5068509 | 0.84 | CA1 (0.75) | MAPTALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL29129887 | 0.84 | MAPT (0.73) | TRPV1MAPTLMNAKMT2AMEN1 | |
| SCHEMBL11245753 | 0.83 | MAPT (0.63) | TRPV1MAPTALDH1A1LMNAKMT2A | |
| SCHEMBL31141615 | 0.82 | HDAC3 (0.66) | TRPV1MAPTLMNAKMT2AMEN1 | |
| SCHEMBL11246781 | 0.82 | FFAR1 (0.60) | MAPTALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL1403476 | 0.82 | KMT2A (0.48) | TRPV1MAPTALDH1A1LMNAKMT2A | |
| SCHEMBL11248670 | 0.81 | HIF1A (0.58) | MAPTCA1CA2HIF1A | |
| SCHEMBL11246229 | 0.81 | MAPT (0.55) | MAPTALDH1A1LMNAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4362892-A | ARALKYLANILINES, ANTICHOLESTEROL AGENTS | BEECHAM GROUP LIMITED (GB) | 1982-12-07 | — | — | US | disclosed |
| US-4206145-A | ALKANOYL-SUBSTITUTED ARALKYLAMINES | BEECHAM GROUP LIMITED (GB) | 1980-06-03 | — | — | US | disclosed |