Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 3/20 | 0.47 |
| ▸ | KCNJ6 | P48051 | 3/20 | 0.43 |
| ▸ | KCNJ3 | P48549 | 3/20 | 0.43 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | FABP3 | P05413 | 3/20 | 0.42 |
| ▸ | FABP4 | P15090 | 3/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 5/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CMKLR1 | Q99788 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11245710 | 0.75 | PTGDR2 (0.51) | PTGDR2 | |
| SCHEMBL5222340 | 0.73 | ESR1 (0.49) | OPRM1OPRD1OPRK1ESR1HTR2A | |
| SCHEMBL5216593 | 0.73 | ESR1 (0.50) | CNR1CNR2ESR1CMKLR1 | |
| SCHEMBL5217448 | 0.73 | ESR1 (0.50) | CNR1CNR2ESR1CMKLR1 | |
| Trifezolac SCHEMBL11182574 | 0.72 | KDM4E (0.51) | PTGDR2ESR1 | |
| SCHEMBL11541106 | 0.71 | PTGDR2 (0.54) | PTGDR2 | |
| SCHEMBL5220933 | 0.71 | ESR1 (0.49) | CNR1CNR2ESR1CMKLR1 | |
| SCHEMBL11254272 | 0.70 | PTGDR2 (0.67) | PTGDR2 | |
| SCHEMBL11248019 | 0.70 | CYP1A2 (0.44) | CNR1CNR2PTGDR2 | |
| SCHEMBL5247339 | 0.69 | ESR1 (0.45) | ESR1HTR2AHTR2CHTR2BCMKLR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4325962-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, ANTIDYRETICS | BYK-GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1982-04-20 | — | — | US | disclosed |
| US-4146721-A | ANALGESICS, ANTIINFLAMMATORY AGENTS AND ANTIPYRETICS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1979-03-27 | — | — | US | disclosed |