Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CFTR | P13569 | 2/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11245176 | 0.92 | P2RX7 (0.44) | CYP1A2CYP2C9CYP2C19P2RX7CNR1 | |
| SCHEMBL11251356 | 0.91 | CYP1A2 (0.42) | CYP1A2CYP2C9CYP2C19P2RX7CNR1 | |
| SCHEMBL11249532 | 0.86 | ALDH1A1 (0.46) | CYP1A2CYP2C9CYP2C19P2RX7CNR1 | |
| Trifezolac SCHEMBL11182574 | 0.76 | KDM4E (0.51) | CYP1A2CYP2C9CYP2C19LMNATP53 | |
| SCHEMBL6123601 | 0.75 | CYP2C9 (0.51) | CYP1A2CYP2C9CYP2C19CNR1CNR2 | |
| SCHEMBL1195159 | 0.75 | CYP2C9 (0.62) | CYP1A2CYP2C9CYP2C19P2RX7NPC1 | |
| SCHEMBL11247967 | 0.70 | CYP2C9 (0.56) | CYP1A2CYP2C9CYP2C19P2RX7LMNA | |
| SCHEMBL11254239 | 0.70 | CNR1 (0.47) | CNR1CNR2PTGDR2 | |
| SCHEMBL11699362 | 0.70 | KDM4E (0.55) | CYP1A2CYP2C9CYP2C19L3MBTL1PTGDR2 | |
| SCHEMBL11254211 | 0.68 | CA1 (0.53) | CYP1A2CYP2C9CYP2C19CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4325962-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, ANTIDYRETICS | BYK-GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1982-04-20 | — | — | US | disclosed |
| US-4146721-A | ANALGESICS, ANTIINFLAMMATORY AGENTS AND ANTIPYRETICS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1979-03-27 | — | — | US | disclosed |
| US-4011332-A | RODENTICIDE | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DT) | 1977-03-08 | — | — | US | disclosed |