Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | HTR7 | P34969 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | DRD3 | P35462 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | IGF1R | P08069 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Peraclopone SCHEMBL11255188 | 1.00 | KDM4E (0.53) | KDM4EMAPTMAPK1NPSR1HTR7 | |
| Peraclopone SCHEMBL2110307 | 1.00 | KDM4E (0.53) | KDM4EMAPTMAPK1NPSR1HTR7 | |
| Peraclopone SCHEMBL11266970 | 0.99 | KDM4E (0.52) | KDM4EMAPTMAPK1NPSR1HTR7 | |
| Peraclopone SCHEMBL11251964 | 0.99 | KDM4E (0.52) | KDM4EMAPTMAPK1NPSR1HTR7 | |
| Peraclopone SCHEMBL11266972 | 0.99 | KDM4E (0.52) | KDM4EMAPTMAPK1NPSR1HTR7 | |
| Peraclopone SCHEMBL11251959 | 0.99 | KDM4E (0.52) | KDM4EMAPTMAPK1NPSR1HTR7 | |
| SCHEMBL11255248 | 0.83 | MAPT (0.52) | MAPTMAPK1NPSR1HTTGAA | |
| SCHEMBL11255243 | 0.83 | MAPT (0.52) | MAPTMAPK1NPSR1HTTGAA | |
| Hydrochloric Acid SCHEMBL11247700 | 0.78 | TSHR (0.57) | KDM4EMAPTMAPK1HTR7ALDH1A1 | |
| Hydrochloric Acid SCHEMBL11247706 | 0.78 | TSHR (0.57) | KDM4EMAPTMAPK1HTR7ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4358450-A | FOR DECREASING BLOOD CHOLESTEROL | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-11-09 | — | — | US | claimed |
| US-4358450-A | FOR DECREASING BLOOD CHOLESTEROL | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-11-09 | — | — | US | disclosed |