Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 1/20 | 0.53 |
| ▸ | PYGL | P06737 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | PLCG2 | P16885 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | PCTP | Q9UKL6 | 1/20 | 0.49 |
| ▸ | ABL1 | P00519 | 1/20 | 0.48 |
| ▸ | SRC | P12931 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | SMO | Q99835 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.43 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11235860 | 0.84 | MEN1 (0.47) | NPC1PKMRAB9ATDP1MAPT | |
| SCHEMBL9739800 | 0.79 | GCGR (0.65) | GCGRPYGLPOLBPLCG2NPC1 | |
| SCHEMBL11245158 | 0.79 | GCGR (0.54) | GCGRPYGLPOLBPLCG2NPC1 | |
| SCHEMBL11242722 | 0.78 | GCGR (0.54) | GCGRPYGLPLCG2PCTPTDP1 | |
| SCHEMBL11138807 | 0.78 | GCGR (0.62) | GCGRPYGLPOLBPLCG2NPC1 | |
| SCHEMBL11245808 | 0.77 | GCGR (0.64) | GCGRPYGLPOLBPLCG2NPC1 | |
| SCHEMBL11243565 | 0.76 | GCGR (0.52) | GCGRPYGLPOLBPLCG2NPC1 | |
| SCHEMBL8620555 | 0.76 | TDP1 (0.55) | GCGRPYGLPOLBPLCG2NPC1 | |
| SCHEMBL11396424 | 0.75 | TDP1 (0.59) | GCGRPYGLPOLBPLCG2NPC1 | |
| SCHEMBL8840342 | 0.75 | NPC1 (0.60) | GCGRPYGLPOLBPLCG2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4350706-A | MITICIDES, LARVICIDES | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1982-09-21 | — | — | US | disclosed |