SCHEMBL11257211

SCHEMBL11257211

CNC(=O)/C(=N/O)C(C)(C)n1cncn1

nearest known ligand 0.51

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.51
CYP19A1 P11511 2/20 0.35
MAPT P10636 1/20 0.33
KMT2A Q03164 1/20 0.33
TSHR P16473 1/20 0.33
CYP26A1 O43174 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11252805 1.00 LMNA (0.51) LMNACYP19A1MAPTKMT2ATSHR
Hydrochloric Acid SCHEMBL11263423 0.97 LMNA (0.49) LMNACYP19A1MAPTKMT2ATSHR
SCHEMBL11256401 0.84 LMNA (0.42) LMNACYP19A1TSHR
SCHEMBL11256412 0.84 LMNA (0.42) LMNACYP19A1TSHR
SCHEMBL11252445 0.78 LMNA (0.56) LMNACYP19A1MAPTKMT2ATSHR
SCHEMBL11252453 0.78 LMNA (0.56) LMNACYP19A1MAPTKMT2ATSHR
SCHEMBL11264498 0.75
SCHEMBL11264511 0.75
SCHEMBL11262103 0.73
SCHEMBL11262098 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4353915-A ARTHROPODICIDES, NEMATOCIDES BAYER AKTIENGESELLSCHAFT (DE) 1982-10-12 US claimed