Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.37 |
| ▸ | ACLY | P53396 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 3/20 | 0.32 |
| ▸ | CES1 | P23141 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11254307 | 1.00 | OXER1 (0.37) | OXER1ACLYALOX5FAAHCES1 | |
| SCHEMBL11254309 | 1.00 | OXER1 (0.37) | OXER1ACLYALOX5FAAHCES1 | |
| SCHEMBL11258147 | 1.00 | OXER1 (0.37) | OXER1ACLYALOX5FAAHCES1 | |
| SCHEMBL12477302 | 0.91 | FAAH (0.32) | OXER1ACLYFAAHCES1 | |
| SCHEMBL11254801 | 0.91 | FAAH (0.32) | OXER1ACLYFAAHCES1 | |
| SCHEMBL12477301 | 0.91 | FAAH (0.32) | OXER1ACLYFAAHCES1 | |
| SCHEMBL11254804 | 0.91 | FAAH (0.32) | OXER1ACLYFAAHCES1 | |
| SCHEMBL12477607 | 0.88 | OXER1 (0.38) | OXER1ACLYALOX5 | |
| SCHEMBL12477608 | 0.88 | OXER1 (0.38) | OXER1ACLYALOX5 | |
| SCHEMBL12476456 | 0.88 | OXER1 (0.32) | OXER1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0003663-A2 | Amino-substituted phenyl and heteroaryl compounds, process for their preparation and pharmaceutical compositions containing them | AMERICAN CYANAMID COMPANY (US) | 1979-08-22 | — | — | EP | claimed |
| US-4318914-A | Hypolipidemic and antiatherosclerotic 4-(polyfluoro-alkylamino)phenyl compounds | AMERICAN CYANAMID COMPANY (US) | 1982-03-09 | — | — | US | disclosed |
| US-4310545-A | Hypolipidemic and antiatherosclerotic 4-(polyfluoroalkylamino) phenyl compounds | AMERICAN CYANAMID COMPANY (US) | 1982-01-12 | — | — | US | disclosed |
| US-4305959-A | Hypolipidemic and antiatherosclerotic 4-(polyfluoro-alkylamino)phenyl compounds | AMERICAN CYANAMID COMPANY (US) | 1981-12-15 | — | — | US | disclosed |
| US-4205085-A | Hypolipidemic and antiatherosclerotic 4-(polyfluoroalkylamino)phenyl compounds | AMERICAN CYANAMID COMPANY (US) | 1980-05-27 | — | — | US | disclosed |
| EP-0003663-A2 | Amino-substituted phenyl and heteroaryl compounds, process for their preparation and pharmaceutical compositions containing them | AMERICAN CYANAMID COMPANY (US) | 1979-08-22 | — | — | EP | disclosed |