Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | QPCT | Q16769 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11261648 | 0.90 | POLB (0.40) | POLBCTDSP1TDP1KMT2ATSHR | |
| SCHEMBL11259565 | 0.90 | POLB (0.38) | POLBCTDSP1TDP1KMT2ATSHR | |
| SCHEMBL11257083 | 0.89 | POLB (0.43) | POLBCTDSP1TDP1KMT2ATSHR | |
| SCHEMBL11262248 | 0.88 | POLB (0.42) | POLBCTDSP1TDP1KMT2ATSHR | |
| SCHEMBL11253666 | 0.86 | POLB (0.44) | POLBCTDSP1TDP1KMT2ATSHR | |
| SCHEMBL11261780 | 0.86 | CYP19A1 (0.43) | POLBCTDSP1TDP1KMT2ACYP11B1 | |
| SCHEMBL11262650 | 0.84 | POLB (0.36) | POLBCTDSP1TDP1KMT2ATSHR | |
| SCHEMBL11261369 | 0.84 | CYP11B1 (0.43) | POLBCTDSP1TDP1KMT2ACYP11B1 | |
| SCHEMBL11252157 | 0.83 | FNTA (0.38) | KMT2AALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11266844 | 0.83 | POLB (0.44) | POLBCTDSP1TDP1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4359475-A | SPERMICIDES, MICROBIOCIDES OR ANTICONVULSANTS | SYNTEX (U.S.A.) INC. (US) | 1982-11-16 | — | — | US | disclosed |