Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
| ▸ | QPCT | Q16769 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | PRKCI | P41743 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11262883 | 0.94 | QPCT (0.42) | CYP19A1CYP11B1CYP11B2QPCTPOLB | |
| SCHEMBL11260023 | 0.93 | QPCT (0.38) | CYP19A1CYP11B1CYP11B2QPCTALDH1A1 | |
| SCHEMBL11271370 | 0.91 | HMOX1 (0.44) | CYP19A1CYP11B1CYP11B2ALDH1A1KDM4E | |
| SCHEMBL11267271 | 0.91 | CYP19A1 (0.42) | CYP19A1CYP11B1CYP11B2QPCT | |
| SCHEMBL11258901 | 0.91 | CYP2A6 (0.43) | CYP19A1CYP11B1CYP11B2KDM4E | |
| SCHEMBL11253358 | 0.91 | CYP19A1 (0.37) | CYP19A1TBXAS1KMT2A | |
| SCHEMBL11255025 | 0.90 | TBXAS1 (0.40) | CYP19A1CYP11B1CYP11B2QPCTPOLB | |
| SCHEMBL11265825 | 0.90 | CYP19A1 (0.40) | CYP19A1CYP11B1CYP11B2QPCTPOLB | |
| SCHEMBL11262886 | 0.90 | CYP19A1 (0.41) | CYP19A1CYP11B1CYP11B2QPCTPOLB | |
| SCHEMBL11261369 | 0.89 | CYP11B1 (0.43) | CYP19A1CYP11B1CYP11B2POLBCTDSP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4359475-A | SPERMICIDES, MICROBIOCIDES OR ANTICONVULSANTS | SYNTEX (U.S.A.) INC. (US) | 1982-11-16 | — | — | US | disclosed |