SCHEMBL1125849

SCHEMBL1125849

CC(C)(C)C1CCC(OOC(=O)OC(=O)OC2CCC(C(C)(C)C)CC2)CC1.[KH]

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.42
APOBEC3A P31941 1/20 0.41
APOBEC3G Q9HC16 1/20 0.41
SMN1; SMN2 Q16637 2/20 0.40
HTT P42858 2/20 0.40
KDM4E B2RXH2 1/20 0.40
CYP19A1 P11511 1/20 0.40
NPC1 O15118 2/20 0.38
RAB9A P51151 2/20 0.38
GAA P10253 1/20 0.36
EPHX1 P07099 1/20 0.33
GLA P06280 1/20 0.32
HSD11B1 P28845 1/20 0.32
LIPA P38571 1/20 0.31
CYP2D6 P10635 1/20 0.30
KCNH2 Q12809 1/20 0.30
HRH3 Q9Y5N1 1/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL975283 0.98 MAPT (0.43) MAPTAPOBEC3AAPOBEC3GSMN1; SMN2HTT
SCHEMBL2299719 0.90 MAPT (0.46) MAPTAPOBEC3AAPOBEC3GSMN1; SMN2HTT
SCHEMBL8727040 0.88 MAPT (0.50) MAPTAPOBEC3AAPOBEC3GSMN1; SMN2HTT
SCHEMBL22733770 0.84 MAPT (0.42) MAPTAPOBEC3AAPOBEC3GSMN1; SMN2HTT
SCHEMBL2980340 0.81 MAPT (0.39) MAPTAPOBEC3AAPOBEC3GSMN1; SMN2HTT
SCHEMBL35809 0.81 MAPT (0.50) MAPTAPOBEC3AAPOBEC3GSMN1; SMN2HTT
SCHEMBL22733771 0.80 MAPT (0.53) MAPTAPOBEC3AAPOBEC3GSMN1; SMN2HTT
SCHEMBL30317531 0.80 MAPT (0.46) MAPTAPOBEC3AAPOBEC3GSMN1; SMN2HTT
SCHEMBL1820747 0.78 MAPT (0.47) MAPTAPOBEC3AAPOBEC3GSMN1; SMN2HTT
SCHEMBL2380073 0.77 MAPT (0.50) MAPTAPOBEC3AAPOBEC3GSMN1; SMN2HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9187577-B2 Filled nanoparticles having an alkylene carbonate core and polymeric shell BATTELLE MEMORIAL INSTITUTE (US) 2015-11-17 US disclosed
EP-2283047-B1 FILLED NANOPARTICLES BATTELLE MEMORIAL INSTITUTE (US) 2014-05-21 EP disclosed
US-20110104495-A1 Filled Nanoparticles BATTELLE MEMORIAL INSTITUTE 2011-05-05 US disclosed
EP-2283047-A1 FILLED NANOPARTICLES Battelle Memorial Institute (US) 2011-02-16 EP disclosed
WO-2009146252-A1 FILLED NANOPARTICLES BATTELLE MEMORIAL INSTITUTE (US) 2009-12-03 WO disclosed
US-7157526-B2 Aqueous primary dispersion, substantially or completely devoid of volatile organic substances, method for the production thereof and use of the same BASF COATINGS AG (DE) 2007-01-02 US disclosed
US-20040048968-A1 Aqueous primary dispersion, substantially or completely devoid of volatile organic substances, method for the production thereof and use of the same BASF COATINGS AKTIENGESELLSCHAFT (DE) 2004-03-11 US disclosed