Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.31 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.31 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.31 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6749053 | 0.70 | GSK3A (0.39) | — | |
| SCHEMBL28475407 | 0.68 | — | — | |
| Hydrochloric Acid SCHEMBL27848734 | 0.66 | — | — | |
| SCHEMBL8633140 | 0.65 | SRC (0.33) | SIRT2SIRT1SIRT3SIRT5 | |
| SCHEMBL17558815 | 0.61 | ADORA2A (0.35) | MAPTSIRT2SIRT1SIRT3SIRT5 | |
| SCHEMBL11875716 | 0.61 | — | — | |
| SCHEMBL9670265 | 0.60 | KDM4E (0.60) | MAPT | |
| SCHEMBL9652276 | 0.60 | KMT2A (0.42) | MAPTADORA3ADORA1TBXAS1 | |
| SCHEMBL8647302 | 0.60 | — | — | |
| SCHEMBL11459169 | 0.59 | KDM4E (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4348518-A | Cephalosporins | HOFFMANN-LA ROCHE INC. (US) | 1982-09-07 | — | — | US | disclosed |
| US-4091211-A | ANTIBIOTICS | HOFFMANN-LA ROCHE INC. (US) | 1978-05-23 | — | — | US | disclosed |