Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.32 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.32 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.32 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 2/20 | 0.30 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2200862 | 0.82 | ALDH1A1 (0.48) | NPC1RAB9AALDH1A1TSHRFGFR1 | |
| SCHEMBL23801986 | 0.76 | — | — | |
| SCHEMBL7822134 | 0.75 | ALDH1A1 (0.44) | NPC1RAB9AALDH1A1TSHRCYP19A1 | |
| SCHEMBL2201604 | 0.75 | CYP3A4 (0.39) | NPC1RAB9AALDH1A1SMN1; SMN2CYP19A1 | |
| SCHEMBL23801952 | 0.74 | ALDH1A1 (0.32) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL1279836 | 0.74 | ALDH1A1 (0.58) | ALDH1A1TSHRCYP19A1 | |
| SCHEMBL20865065 | 0.74 | ALDH1A1 (0.50) | ALDH1A1TSHRCYP19A1 | |
| SCHEMBL11261073 | 0.72 | ALDH1A1 (0.55) | ALDH1A1TSHRCYP19A1 | |
| SCHEMBL2201853 | 0.72 | ALDH1A1 (0.37) | NPC1RAB9AALDH1A1FGFR1FGFR2 | |
| SCHEMBL16803093 | 0.71 | KDM1A (0.40) | NPC1RAB9AALDH1A1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4341906-A | ANALGESICS | PFIZER INC. (US) | 1982-07-27 | — | — | US | disclosed |
| US-4310669-A | TETRALONE | PFIZER INC. (US) | 1982-01-12 | — | — | US | disclosed |
| US-4310668-A | Intermediates to 1,9-dihydroxyoctahydrophenanthrenes | PFIZER INC. (US) | 1982-01-12 | — | — | US | disclosed |
| US-4310529-A | ANALGESICS | PFIZER INC. (US) | 1982-01-12 | — | — | US | disclosed |
| US-4270005-A | ANALGESICS | PFIZER INC. (US) | 1981-05-26 | — | — | US | disclosed |
| US-4268523-A | ANALGESICS | PFIZER INC. (US) | 1981-05-19 | — | — | US | disclosed |
| US-4268692-A | ANALGESICS | PFIZER INC. (US) | 1981-05-19 | — | — | US | disclosed |
| US-4237133-A | ANALGESICS | PFIZER INC. (US) | 1980-12-02 | — | — | US | disclosed |
| US-4188495-A | 1,9-Dihydroxyoctahydrophenanthrenes and intermediates therefor | PFIZER INC. (US) | 1980-02-12 | — | — | US | disclosed |