Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.86 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.68 |
| ▸ | POLB | P06746 | 2/20 | 0.66 |
| ▸ | MEN1 | O00255 | 6/20 | 0.61 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.61 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.53 |
| ▸ | RELA | Q04206 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | AURKA | O14965 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23392558 | 0.94 | PTGS2 (0.86) | PTGS2KMT2AALDH1A1SMN1; SMN2POLB | |
| SCHEMBL3447906 | 0.89 | PTGS2 (1.00) | PTGS2KMT2AALDH1A1SMN1; SMN2POLB | |
| SCHEMBL28358360 | 0.86 | PTGS2 (0.94) | PTGS2KMT2AALDH1A1SMN1; SMN2POLB | |
| SCHEMBL20718854 | 0.86 | PTGS2 (0.86) | PTGS2KMT2AALDH1A1SMN1; SMN2POLB | |
| SCHEMBL12922059 | 0.86 | PTGS2 (0.86) | PTGS2KMT2AALDH1A1SMN1; SMN2POLB | |
| SCHEMBL11243639 | 0.85 | POLB (0.89) | PTGS2KMT2AALDH1A1SMN1; SMN2POLB | |
| SCHEMBL1004409 | 0.85 | PTGS2 (0.80) | PTGS2KMT2AALDH1A1SMN1; SMN2POLB | |
| SCHEMBL11260604 | 0.85 | PTGS2 (0.80) | PTGS2KMT2AALDH1A1SMN1; SMN2POLB | |
| SCHEMBL15987959 | 0.84 | PTGS2 (0.69) | PTGS2KMT2AALDH1A1SMN1; SMN2POLB | |
| SCHEMBL19652416 | 0.83 | PTGS2 (0.76) | PTGS2KMT2AALDH1A1SMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4325962-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, ANTIDYRETICS | BYK-GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1982-04-20 | — | — | US | disclosed |
| US-4146721-A | ANALGESICS, ANTIINFLAMMATORY AGENTS AND ANTIPYRETICS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1979-03-27 | — | — | US | disclosed |