Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX4 | Q99571 | 1/20 | 0.56 |
| ▸ | SRC | P12931 | 2/20 | 0.55 |
| ▸ | TYMP | P19971 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.45 |
| ▸ | GSK3A | P49840 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11792243 | 0.78 | P2RX4 (0.59) | P2RX4SRCTYMPIDO1ELANE | |
| SCHEMBL11590471 | 0.76 | P2RX4 (0.67) | P2RX4SRCIDO1ELANEMEN1 | |
| SCHEMBL28381737 | 0.73 | P2RX4 (0.53) | P2RX4SRCTYMPIDO1MEN1 | |
| SCHEMBL3015728 | 0.72 | TYMP (0.54) | P2RX4SRCTYMPIDO1ELANE | |
| SCHEMBL872109 | 0.72 | P2RX4 (0.81) | P2RX4SRCIDO1ELANEMEN1 | |
| SCHEMBL12611492 | 0.72 | P2RX4 (1.00) | P2RX4SRCIDO1MEN1KMT2A | |
| SCHEMBL7980254 | 0.71 | SRC (1.00) | P2RX4SRCIDO1MEN1KMT2A | |
| SCHEMBL859906 | 0.71 | TSHR (0.48) | MEN1KMT2ASMN1; SMN2HPGDKDM4E | |
| SCHEMBL11003826 | 0.70 | CYP3A4 (0.57) | P2RX4SRCTYMPIDO1MEN1 | |
| SCHEMBL31621004 | 0.69 | TYMP (0.60) | P2RX4SRCTYMPIDO1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0010441-B1 | THE USE OF SYMMETRICALLY SUBSTITUTED PYROMELLITIC DIIMIDES AS RUMINANT FEED ADDITIVES. COMPOSITIONS CONTAINING THESE FEED ADDITIVES | MERCK & CO. INC. (US) | 1982-04-21 | — | — | EP | disclosed |
| US-4212880-A | INCREASE FEED EFFICIENCY | MERCK & CO., INC. (US) | 1980-07-15 | — | — | US | disclosed |
| EP-0010441-A1 | The use of symmetrically substituted pyromellitic diimides as ruminant feed additives. Compositions containing these feed additives | MERCK & CO. INC. (US) | 1980-04-30 | — | — | EP | disclosed |