SCHEMBL859906

SCHEMBL859906

O=C(On1c(=O)c2cc3c(=O)n(OC(=O)c4ccccc4)c(=O)c3cc2c1=O)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.48
LMNA P02545 5/20 0.47
F2 P00734 1/20 0.47
KMT2A Q03164 8/20 0.43
KDM4E B2RXH2 4/20 0.43
PLA2G1B P04054 2/20 0.43
ATG4B Q9Y4P1 2/20 0.43
MAPT P10636 3/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
ALDH1A1 P00352 4/20 0.41
NPSR1 Q6W5P4 1/20 0.41
HTT P42858 1/20 0.41
TDP1 Q9NUW8 3/20 0.40
TP53 P04637 2/20 0.40
MEN1 O00255 1/20 0.40
POLB P06746 2/20 0.39
MAPK1 P28482 1/20 0.39
HIF1A Q16665 1/20 0.39
GAA P10253 1/20 0.39
SLC6A2 P23975 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13604060 0.82 KMT2A (0.42) TSHRLMNAKMT2AKDM4EPLA2G1B
SCHEMBL2238063 0.80 LMNA (0.54) TSHRLMNAF2KMT2AMAPT
SCHEMBL27800832 0.76 F2 (0.48) TSHRLMNAF2KMT2AKDM4E
SCHEMBL4022180 0.76 LMNA (0.48) TSHRLMNAF2KMT2AMAPT
SCHEMBL13701356 0.75 ALDH1A1 (0.42) KMT2AKDM4EMAPTSMN1; SMN2ALDH1A1
SCHEMBL4023905 0.74 TSHR (0.48) TSHRLMNAF2KMT2AMAPT
SCHEMBL3506128 0.73 TSHR (0.52) TSHRLMNAF2KMT2AKDM4E
SCHEMBL859907 0.71 CA12 (0.47) KMT2AKDM4EMAPTSMN1; SMN2ALDH1A1
SCHEMBL11258768 0.71 P2RX4 (0.56) TSHRLMNAKMT2AKDM4EMAPT
SCHEMBL1232166 0.69 LMNA (0.50) TSHRLMNAF2KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8142983-B2 Lithographic printing plate precursor and method of lithographic printing FUJIFILM CORPORATION (JP) 2012-03-27 US disclosed
US-8142983-B2 Lithographic printing plate precursor and method of lithographic printing FUJIFILM CORPORATION (JP) 2012-03-27 US disclosed
EP-1666551-B1 Ink for ink jet-recording curable through irradiation and method for preparing lithographic printing plates using the same FUJIFILM CORP (JP) 2010-02-17 EP disclosed
US-7635181-B2 Ink for ink jet-recording curable through irradiation with a radioactive ray and method for preparing lithographic printing plates using the same FUJIFILM CORPORATION (JP) 2009-12-22 US disclosed
US-7635181-B2 Ink for ink jet-recording curable through irradiation with a radioactive ray and method for preparing lithographic printing plates using the same FUJIFILM CORPORATION (JP) 2009-12-22 US disclosed
US-20090233229-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD OF LITHOGRAPHIC PRINTING FUJIFILM CORPORATION (JP) 2009-09-17 US disclosed
US-20090233229-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD OF LITHOGRAPHIC PRINTING FUJIFILM CORPORATION (JP) 2009-09-17 US disclosed
EP-2100731-A2 Lithographic printing plate precursor and method of lithographic printing Fujifilm Corporation (JP) 2009-09-16 EP disclosed