Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | FBP1 | P09467 | 7/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | LATS1 | O95835 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11269616 | 0.89 | PPARA (0.44) | PPARAPPARGABCB11CYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL11267416 | 0.88 | PPARG (0.44) | PPARAPPARG | |
| SCHEMBL11255207 | 0.88 | PPARA (0.41) | PPARAPPARGABCB11CYP1A2CYP3A4 | |
| SCHEMBL11257510 | 0.85 | PPARA (0.41) | PPARAPPARGABCB11CYP1A2CYP3A4 | |
| SCHEMBL11249243 | 0.84 | PPARA (0.42) | PPARAPPARGABCB11CYP1A2CYP3A4 | |
| SCHEMBL11265797 | 0.84 | PPARA (0.45) | PPARAPPARGABCB11CYP1A2CYP3A4 | |
| SCHEMBL11259439 | 0.83 | KDM4E (0.45) | PPARAPPARGABCB11CYP1A2CYP3A4 | |
| SCHEMBL11265214 | 0.82 | PPARA (0.44) | PPARAPPARGABCB11CYP1A2CYP3A4 | |
| SCHEMBL11263819 | 0.80 | ATM (0.47) | PPARAPPARGABCB11CYP1A2CYP3A4 | |
| SCHEMBL11290711 | 0.79 | PPARA (0.47) | PPARAPPARGABCB11CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4343811-A | ATHEROSCLEROSIS | BOEHRINGER INGELHEIM GMBH (DE) | 1982-08-10 | — | — | US | disclosed |