Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 4/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | ACSL1 | P33121 | 2/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | FBP1 | P09467 | 2/20 | 0.36 |
| ▸ | F2RL3 | Q96RI0 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11259060 | 0.89 | PTPN7 (0.40) | PPARAPPARGKMT2AMEN1F2RL3 | |
| SCHEMBL11259129 | 0.88 | PPARA (0.42) | PPARAPPARGELANECYP1A2CYP3A4 | |
| SCHEMBL11269616 | 0.87 | PPARA (0.44) | PPARAPPARGELANECYP1A2CYP3A4 | |
| SCHEMBL11290711 | 0.82 | PPARA (0.47) | PPARAPPARGELANECYP1A2CYP3A4 | |
| SCHEMBL11257510 | 0.81 | PPARA (0.41) | PPARAPPARGELANECYP1A2CYP3A4 | |
| SCHEMBL11249243 | 0.81 | PPARA (0.42) | PPARAPPARGELANECYP1A2CYP3A4 | |
| SCHEMBL11265214 | 0.80 | PPARA (0.44) | PPARAPPARGELANECYP1A2CYP3A4 | |
| SCHEMBL11265797 | 0.80 | PPARA (0.45) | PPARAPPARGELANECYP1A2CYP3A4 | |
| SCHEMBL11265325 | 0.79 | ADORA2B (0.43) | PPARAPPARGCYP1A2CYP3A4ABCB11 | |
| SCHEMBL11266751 | 0.79 | PPARA (0.41) | PPARAPPARGELANECYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4343811-A | ATHEROSCLEROSIS | BOEHRINGER INGELHEIM GMBH (DE) | 1982-08-10 | — | — | US | disclosed |