Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.68 |
| ▸ | MAPT | P10636 | 2/20 | 0.68 |
| ▸ | MEN1 | O00255 | 1/20 | 0.68 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.68 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.68 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.68 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.68 |
| ▸ | HTR2B | P41595 | 1/20 | 0.68 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.68 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.68 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | CNR1 | P21554 | 3/20 | 0.50 |
| ▸ | CNR2 | P34972 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11461787 | 1.00 | LMNA (0.68) | LMNACYP3A4MAPTMEN1NR1I2 | |
| SCHEMBL15766880 | 1.00 | LMNA (0.68) | LMNACYP3A4MAPTMEN1NR1I2 | |
| SCHEMBL5055118 | 0.94 | LMNA (0.59) | LMNACYP3A4MAPTMEN1NR1I2 | |
| SCHEMBL5052356 | 0.89 | LMNA (0.53) | LMNACYP3A4MAPTMEN1NR1I2 | |
| SCHEMBL11441352 | 0.88 | LMNA (0.72) | LMNACYP3A4MAPTMEN1NR1I2 | |
| SCHEMBL11345796 | 0.88 | LMNA (0.72) | LMNACYP3A4MAPTMEN1NR1I2 | |
| SCHEMBL11441656 | 0.86 | LMNA (0.70) | LMNACYP3A4MAPTMEN1NR1I2 | |
| SCHEMBL10625439 | 0.86 | LMNA (0.70) | LMNACYP3A4MAPTMEN1NR1I2 | |
| SCHEMBL3517531 | 0.84 | KMT2A (0.72) | LMNACYP3A4MAPTMEN1NR1I2 | |
| SCHEMBL28200555 | 0.84 | LMNA (0.68) | LMNACYP3A4MAPTMEN1NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4362878-A | DEVELOPMENT INHIBITOR RELEASE AGENTS | CIBA-GEIGY AG (CH) | 1982-12-07 | — | — | US | disclosed |
| US-4259437-A | EXCELLENT INTRA-IMAGE AND INTER-IMAGE EFFECTS OF EXCELLENT SPEED | CIBA-GEIGY AG (CH) | 1981-03-31 | — | — | US | disclosed |
| US-4237281-A | Dyestuffs containing amino or imino groups | CIBA-GEIGY AKTIENGESELLSCHAFT (CH) | 1980-12-02 | — | — | US | disclosed |
| US-4226934-A | SILVER HALIDE EMULSIONS, HETERO-HETEROTHIOACETOPHENONES | CIBA-GEIGY AG (CH) | 1980-10-07 | — | — | US | disclosed |
| US-4059447-A | Photographic material containing oxazolinone-2 couplers | AGFA-GEVAERT AKTIENGESELLSCHAFT (DT) | 1977-11-22 | — | — | US | disclosed |