Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | L3MBTL3 | Q96JM7 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.48 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.47 |
| ▸ | NPY2R | P49146 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzylic Acid SCHEMBL28790412 | 0.78 | CHRM3 (0.54) | KDM4EALDH1A1L3MBTL1SIGMAR1 | |
| Benzoic Acid SCHEMBL28780998 | 0.78 | L3MBTL3 (0.64) | KDM4EALDH1A1L3MBTL3L3MBTL1POLB | |
| SCHEMBL22171622 | 0.77 | CHRM3 (0.57) | — | |
| Phenol SCHEMBL1846721 | 0.75 | SLC18A3 (0.58) | KDM4EALDH1A1L3MBTL3L3MBTL1POLB | |
| Benzamide SCHEMBL1846990 | 0.75 | L3MBTL3 (0.60) | KDM4EALDH1A1L3MBTL3L3MBTL1POLB | |
| Benzylic Acid SCHEMBL27924962 | 0.74 | CHRM3 (0.51) | KEAP1NFE2L2 | |
| Bicarbonate SCHEMBL19689366 | 0.74 | L3MBTL3 (0.50) | KDM4EALDH1A1L3MBTL3L3MBTL1POLB | |
| Bicarbonate SCHEMBL11101479 | 0.74 | L3MBTL3 (0.50) | KDM4EALDH1A1L3MBTL3L3MBTL1POLB | |
| Benzylic Acid SCHEMBL7066 | 0.74 | CYP2C9 (0.74) | ALDH1A1L3MBTL1KEAP1NFE2L2 | |
| SCHEMBL8507450 | 0.74 | NPC1 (0.47) | KDM4EALDH1A1L3MBTL1KEAP1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4353922-A | DERIVATIVES OF 7-AZABICYCLO(2,2,1)HEPTANE | SYNTEX (U.S.A.) INC. (US) | 1982-10-12 | — | — | US | disclosed |