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L3MBTL3

Lethal(3)malignant brain tumor-like protein 3 · Q96JM7 · L3MBTL3 on Sugi Atlas →

28,532 patent compounds predicted against L3MBTL3, 16,359 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL95490 SCHEMBL95490 0.85 19/20
SCHEMBL590136 SCHEMBL590136 0.79 19/20
SCHEMBL310733 SCHEMBL310733 0.53 19/20
SCHEMBL117191 SCHEMBL117191 0.52 19/20
SCHEMBL279856 SCHEMBL279856 0.81 18/20
SCHEMBL425626 SCHEMBL425626 0.56 18/20
SCHEMBL96138 SCHEMBL96138 0.54 18/20
SCHEMBL277178 SCHEMBL277178 0.79 17/20
SCHEMBL77669 SCHEMBL77669 0.79 16/20
SCHEMBL488181 SCHEMBL488181 0.60 16/20
SCHEMBL422889 SCHEMBL422889 0.58 16/20
SCHEMBL310306 SCHEMBL310306 0.55 16/20
SCHEMBL589777 SCHEMBL589777 0.50 16/20
SCHEMBL95807 SCHEMBL95807 0.68 15/20
SCHEMBL310165 SCHEMBL310165 0.60 15/20
Hydrochloric Acid Hydrochloric Acid (SCHEMBL457517) 0.56 15/20
SCHEMBL309496 SCHEMBL309496 0.51 15/20
SCHEMBL310663 SCHEMBL310663 0.51 15/20
SCHEMBL422654 SCHEMBL422654 0.50 15/20
SCHEMBL94754 SCHEMBL94754 0.79 14/20

Clinical trials — most relevant to L3MBTL3 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
ONC201 in Recurrent/Refractory Metastatic Breast Cancer and Advanced Endometrial Carcinoma PHASE2COMPLETED
MiRNA223 and HMGB1 as Apredictos for Drug Resistant Epilepsy nanUNKNOWN
Epitranscriptomic Blood Biomarkers for Coronary Artery Disease - A Prospective Cohort Study (IHD-EPITRAN) nanUNKNOWN
Aberrant Splicings Due to Microsatellite Instability in Colorectal Cancer : Physiopathological and Clinical Impact nanUNKNOWN
Role of SF3B1 Mutation in Assessment of Acute and Chronic Lymphatic Leukemia nanNOT_YET_RECRUITING
Association of SNPs in Long Intergenic Noncoding RNA 00511 (LINC00511) With Breast Cancer Among the Egyptian Population nanCOMPLETED
The Value of circRNAs (hsa_circ_0004001) in Early Diagnosis of HCC nanUNKNOWN
LINC00511/miR-185-3p Axis and miR-301a-3p Markers for Breast Cancer Diagnosis nanCOMPLETED
Prevalence of a Non-Expressing 11B Mutation in Aka Peoples of the Central African Republic nanCOMPLETED
Identification of Genetic Variants Associated With Unexpected Infant Death Syndrome nanRECRUITING
Sperm Epigenome in Hodgkin Lymphoma nanNOT_YET_RECRUITING
Patient's Derived Organoids for Drug Screening in Glioblastoma nanNOT_YET_RECRUITING
MicroRNAs and Cytokines in Peri-Implantitis Tissue nanUNKNOWN
Research on Effects of Acute Consumption of Nuts in Obese Diabetic Women nanRECRUITING
MicroRNA-1 (miRNA-1) and MicroRNA-133a (miRNA-133a) Levels After Acute Exercise in Ultimate Frisbee Athletes nanUNKNOWN
Establishment of Human Cellular Disease Models for Wilson Disease nanCOMPLETED
Prognostic Value of Protein IMP3 Expression in Cervical Cancer nanCOMPLETED
SMN Circular RNAs as Potential Biomarkers for the Therapeutic Response to Nusinersen in Spinal Muscular Atrophy Patients nanUNKNOWN
Impact of Weight Loss on the Human Sperm Epitranscriptome nanACTIVE_NOT_RECRUITING
Maternal Genes and Epimutations: Beckwith-Wiedemann Syndrome & Reproductive Risks nanRECRUITING
SMYD3-Driven Metabolic Rewiring in Colorectal Liver Metastases nanNOT_YET_RECRUITING
Timisnar - Biomarkers Substudy (Timisnar-mirna) nanUNKNOWN
Long Term Monitoring for Risk of Sudden Death nanCOMPLETED
Genetic Factors Affecting the Severity of Beta Thalassemia nanCOMPLETED
Lung Cancer Diagnosis by Detecting Epigenetic Imprinting Alterations in Bronchoalveolar Lavage nanUNKNOWN
Genetics of Familial and Sporadic ALS nanCOMPLETED
Immunophenotyping and Xist Gene in AML nanUNKNOWN
miR-155 Expression in Episodic and Chronic Migraine nanUNKNOWN
Uncovering Genes Behind Cartilage Tumors and Vascular Anomalies Using Genomic Sequencing nanRECRUITING
UW Undiagnosed Genetic Diseases Program nanRECRUITING

Related proteins — ESM-2 sequence neighbours (a L3MBTL3 binder may also engage these)

ProteinNameSimilarity
E1C2V1 — 1.000 E1C2V1 →
B1B1A0 — 0.999 B1B1A0 →
Q5TKR9 — 0.996 Q5TKR9 →
L3MBTL4 Lethal(3)malignant brain tumor-like protein 4 0.995 landscape →
Q8BLB7 — 0.995 Q8BLB7 →
A2A5N8 — 0.995 A2A5N8 →
Q8WML3 — 0.993 Q8WML3 →
Q8BZ21 — 0.992 Q8BZ21 →
KDM4B Lysine-specific demethylase 4B 0.992 landscape →
Q8VCD7 — 0.992 Q8VCD7 →
KAT6B Histone acetyltransferase KAT6B 0.992 landscape →
D3ZWK4 — 0.991 D3ZWK4 →
Q6ZUT3 — 0.991 Q6ZUT3 →
Q92539 — 0.991 Q92539 →
Q28D84 — 0.991 Q28D84 →
Q63553 — 0.991 Q63553 →
Q92613 — 0.990 Q92613 →
Q4V863 — 0.990 Q4V863 →
Q8K3E5 — 0.990 Q8K3E5 →
A2AD83 — 0.990 A2AD83 →
Q28Z18 — 0.990 Q28Z18 →
Q24K09 — 0.989 Q24K09 →
O70445 — 0.989 O70445 →
L3MBTL1 Lethal(3)malignant brain tumor-like protein 1 0.989 landscape →
MAP3K13 Mitogen-activated protein kinase kinase kinase 13 0.989 landscape →
Q6ZPJ3 — 0.989 Q6ZPJ3 →
G5E8B9 — 0.989 G5E8B9 →
P58270 — 0.989 P58270 →
KAT8 Histone acetyltransferase KAT8 0.989 landscape →
Q32KD2 — 0.989 Q32KD2 →