SCHEMBL11259548

SCHEMBL11259548

CCCCCCCCCCCCCCCCCCNCC(C)(C)S

nearest known ligand 0.52

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.52
ALDH1A1 P00352 1/20 0.52
EPHX1 P07099 9/20 0.43
ADH1B P00325 1/20 0.43
ADH1C P00326 1/20 0.43
ADH1A P07327 1/20 0.43
ADH4 P08319 1/20 0.43
ADH7 P40394 1/20 0.43
S1PR2 O95136 5/20 0.39
S1PR4 O95977 5/20 0.39
S1PR1 P21453 5/20 0.39
S1PR3 Q99500 5/20 0.39
S1PR5 Q9H228 1/20 0.39
THRB P10828 1/20 0.36
HRH4 Q9H3N8 1/20 0.35
HRH3 Q9Y5N1 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7792166 0.98 TSHR (0.50) TSHRALDH1A1EPHX1ADH1BADH1C
SCHEMBL5733012 0.86 TSHR (0.38) TSHRALDH1A1
SCHEMBL17119221 0.83 CYP2C19 (0.36) TSHRALDH1A1
SCHEMBL8416880 0.81 TSHR (0.57) TSHRALDH1A1EPHX1ADH1BADH1C
SCHEMBL8418522 0.81 TSHR (0.57) TSHRALDH1A1EPHX1ADH1BADH1C
SCHEMBL8521009 0.81 TSHR (0.57) TSHRALDH1A1EPHX1ADH1BADH1C
SCHEMBL8420290 0.81 TSHR (0.57) TSHRALDH1A1EPHX1ADH1BADH1C
SCHEMBL17526606 0.81 TSHR (0.57) TSHRALDH1A1EPHX1ADH1BADH1C
SCHEMBL8418749 0.81 TSHR (0.57) TSHRALDH1A1EPHX1ADH1BADH1C
SCHEMBL25887058 0.81 TSHR (0.57) TSHRALDH1A1EPHX1ADH1BADH1C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4332950-A DYE INTERMEDIATES POLAROID CORPORATION (US) 1982-06-01 US disclosed