Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | EPHX1 | P07099 | 9/20 | 0.46 |
| ▸ | ADH1B | P00325 | 1/20 | 0.46 |
| ▸ | ADH1C | P00326 | 1/20 | 0.46 |
| ▸ | ADH1A | P07327 | 1/20 | 0.46 |
| ▸ | ADH4 | P08319 | 1/20 | 0.46 |
| ▸ | ADH7 | P40394 | 1/20 | 0.46 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.42 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.42 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25887058 | 1.00 | TSHR (0.57) | TSHRALDH1A1EPHX1ADH1BADH1C | |
| SCHEMBL8420290 | 1.00 | TSHR (0.57) | TSHRALDH1A1EPHX1ADH1BADH1C | |
| SCHEMBL17526606 | 1.00 | TSHR (0.57) | TSHRALDH1A1EPHX1ADH1BADH1C | |
| SCHEMBL8416880 | 1.00 | TSHR (0.57) | TSHRALDH1A1EPHX1ADH1BADH1C | |
| SCHEMBL8418749 | 1.00 | TSHR (0.57) | TSHRALDH1A1EPHX1ADH1BADH1C | |
| SCHEMBL8521009 | 1.00 | TSHR (0.57) | TSHRALDH1A1EPHX1ADH1BADH1C | |
| SCHEMBL8417470 | 0.97 | TSHR (0.60) | TSHRALDH1A1EPHX1ADH1BADH1C | |
| SCHEMBL10198685 | 0.90 | TSHR (0.52) | TSHRALDH1A1EPHX1ADH1BADH1C | |
| SCHEMBL18536704 | 0.85 | TSHR (0.50) | TSHRALDH1A1ADH1BADH1CADH1A | |
| SCHEMBL11259548 | 0.81 | TSHR (0.52) | TSHRALDH1A1EPHX1ADH1BADH1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5840977-A | CYCLOHEXANOL UREA DERIVATIVE AS INTERMEDIATE | FUJIREBIO INC. (JP) | 1998-11-24 | — | — | US | claimed |
| EP-0612740-A1 | Methods of producing pantothenic acid derivative and its starting materials for producing the same | FUJIREBIO Inc. (JP) | 1994-08-31 | — | — | EP | claimed |
| US-20160039879-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | S&T GLOBAL INC. (US) | 2016-02-11 | — | — | US | disclosed |
| EP-0612740-B1 | Methods of producing pantothenic acid derivative and its starting materials for producing the same | FUJIREBIO KK (JP) | 1999-09-22 | — | — | EP | disclosed |
| US-5840977-A | CYCLOHEXANOL UREA DERIVATIVE AS INTERMEDIATE | FUJIREBIO INC. (JP) | 1998-11-24 | — | — | US | disclosed |
| US-5719298-A | REACTING PANTOTHENIC ACID ACETONIDE WITH UREA COMPOUND IN THE PRESENCE OF ACYLATING AGENT | FUJIREBIO INC. (JP) | 1998-02-17 | — | — | US | disclosed |
| EP-0612740-A1 | Methods of producing pantothenic acid derivative and its starting materials for producing the same | FUJIREBIO Inc. (JP) | 1994-08-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160039879-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | FKBP1B, MALT1, FKBP5 | TSHR 4131/4885ALDH1A1 2376/4885EPHX1 4237/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.