Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4071187 | 0.77 | DGAT1 (0.38) | DGAT1 | |
| SCHEMBL23675088 | 0.76 | DGAT1 (0.37) | DGAT1 | |
| SCHEMBL30298923 | 0.76 | DGAT1 (0.37) | DGAT1 | |
| SCHEMBL10290185 | 0.75 | — | — | |
| SCHEMBL5613238 | 0.75 | — | — | |
| SCHEMBL8926717 | 0.75 | — | — | |
| SCHEMBL18843238 | 0.73 | — | — | |
| SCHEMBL18965731 | 0.73 | DGAT1 (0.38) | DGAT1 | |
| SCHEMBL6759648 | 0.73 | DGAT1 (0.38) | DGAT1 | |
| SCHEMBL1305303 | 0.71 | DGAT1 (0.37) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4329363-A | Substituted mercapto acid amides and their use | MERCK & CO., INC. (US) | 1982-05-11 | — | — | US | disclosed |
| US-4216160-A | IMMUNOREGULANTS FOR CORRECTING AN INBALANCE OF IMMUNE HOMEOSTASIS | MERCK & CO., INC. (US) | 1980-08-05 | — | — | US | disclosed |