⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27541122 | 0.95 | ALDH1A1 (0.43) | — | |
| SCHEMBL104463 | 0.95 | — | — | |
| SCHEMBL9070438 | 0.91 | — | — | |
| SCHEMBL6915443 | 0.91 | — | — | |
| SCHEMBL6913095 | 0.91 | — | — | |
| SCHEMBL6908765 | 0.91 | — | — | |
| SCHEMBL6914939 | 0.91 | — | — | |
| Fluoride SCHEMBL727027 | 0.91 | — | — | |
| SCHEMBL20659151 | 0.91 | — | — | |
| SCHEMBL9737500 | 0.91 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4381536-A | ELECTROLYTE IS AMMONIUM DIFLUOROACETATE DISSOLVED IN ETHYLENE GLYC | SPRAGUE ELECTRIC COMPANY (US) | 1983-04-26 | — | — | US | claimed |
| US-12115467-B2 | Amine separation method using liquid chromatography | DAICEL CORPORATION (JP) | 2024-10-15 | — | — | US | disclosed |
| US-20220339555-A1 | AMINE SEPARATION METHOD USING LIQUID CHROMATOGRAPHY | DAICEL CORPORATION (JP) | 2022-10-27 | — | — | US | disclosed |
| US-20150232616-A1 | HYBRID BLOCK COPOLYMER MICELLES WITH MIXED STEREOCHEMISTRY FOR ENCAPSULATION OF HYDROPHOBIC AGENTS | INTEZYNE TECHNOLOGIES, INC. | 2015-08-20 | — | — | US | disclosed |
| US-8980326-B2 | Hybrid block copolymer micelles with mixed stereochemistry for encapsulation of hydrophobic agents | INTEZYNE TECHNOLOGIES, INC. (US) | 2015-03-17 | — | — | US | disclosed |
| US-8865920-B2 | N-acylation of amines | NOVUS INTERNATIONAL, INC. (US) | 2014-10-21 | — | — | US | disclosed |
| EP-2359862-B1 | Hybrid block copolymer micelles with mixed stereochemistry for encapsulation of hydrophobic agents | INTEZYNE TECHNOLOGIES INC (US) | 2013-07-24 | — | — | EP | disclosed |
| US-20130012728-A1 | N-ACYLATION OF AMINES | NOVUS INTERNATIONAL INC. (US) | 2013-01-10 | — | — | US | disclosed |
| WO-2011112648-A1 | N-ACYLATION OF AMINES | NOVUS INTERNATIONAL INC. (US) | 2011-09-15 | — | — | WO | disclosed |
| EP-2359862-A1 | Hybrid block copolymer micelles with mixed stereochemistry for encapsulation of hydrophobic agents | Intezyne Technologies Inc. (US) | 2011-08-24 | — | — | EP | disclosed |
| US-20100324259-A1 | HYBRID BLOCK COPOLYMER MICELLES WITH MIXED STEREOCHEMISTRY FOR ENCAPSULATION OF HYDROPHOBIC AGENTS | INTEZYNE TECHNOLOGIES, INC. (US) | 2010-12-23 | — | — | US | disclosed |
| EP-2073850-B1 | HYBRID BLOCK COPOLYMER MICELLES WITH MIXED STEREOCHEMISTRY FOR ENCAPSULATION OF HYDROPHOBIC AGENTS | INTEZYNE TECHNOLOGIES INC (US) | 2010-10-27 | — | — | EP | disclosed |
| US-7799339-B2 | Copolymer of crosslinkable or crosslinked poly(amino acid block), and a hydrophobic D,L-mixed poly(amino acid) block; an inner core, crosslinked outer core, a hydrophilic shell; improved in vivo circulation time; drug delivery | INTEZYNE TECHNOLOGIES, INC. (US) | 2010-09-21 | — | — | US | disclosed |
| US-20090286938-A1 | SYNTHESIS OF HYBRID BLOCK COPOLYMERS FROM DIFLUOROACETATE AMMONIUM SALTS | INTEZYNE TECHNOLOGIES, INC. (US) | 2009-11-19 | — | — | US | disclosed |
| WO-2009134984-A1 | SYNTHESIS OF HYBRID BLOCK COPOLYMERS FROM DIFLUOROACETATE AMMONIUM SALTS | INTEZYNE TECHNOLGIES INC. (US) | 2009-11-05 | — | — | WO | disclosed |
| EP-2073850-A1 | HYBRID BLOCK COPOLYMER MICELLES WITH MIXED STEREOCHEMISTRY FOR ENCAPSULATION OF HYDROPHOBIC AGENTS | Intezyne Technologies Incorporated (US) | 2009-07-01 | — | — | EP | disclosed |
| US-20080274173-A1 | Copolymer of crosslinkable or crosslinked poly(amino acid block), and a hydrophobic D,L-mixed poly(amino acid) block; an inner core, crosslinked outer core, a hydrophilic shell; improved in vivo circulation time; drug delivery | INTEZYNE TECHNOLOGIES, INC. (US) | 2008-11-06 | — | — | US | disclosed |
| WO-2008134731-A1 | HYBRID BLOCK COPOLYMER MICELLES WITH MIXED STEREOCHEMISTRY FOR ENCAPSULATION OF HYDROPHOBIC AGENTS | INTEZYNE TECHNOLOGIES, INC. (US) | 2008-11-06 | — | — | WO | disclosed |
| US-4381536-A | ELECTROLYTE IS AMMONIUM DIFLUOROACETATE DISSOLVED IN ETHYLENE GLYC | SPRAGUE ELECTRIC COMPANY (US) | 1983-04-26 | — | — | US | disclosed |
| US-4381536-A | ELECTROLYTE IS AMMONIUM DIFLUOROACETATE DISSOLVED IN ETHYLENE GLYC | SPRAGUE ELECTRIC COMPANY (US) | 1983-04-26 | — | — | US | disclosed |