Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 6/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 4/20 | 0.39 |
| ▸ | CA1 | P00915 | 4/20 | 0.39 |
| ▸ | CA2 | P00918 | 4/20 | 0.39 |
| ▸ | CA4 | P22748 | 4/20 | 0.39 |
| ▸ | CA9 | Q16790 | 4/20 | 0.39 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.37 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11274442 | 0.88 | PTGS2 (0.50) | PTGS1PTGS2LMNATSHRCA12 | |
| SCHEMBL11408289 | 0.85 | PTGS2 (0.51) | PTGS1PTGS2LMNACA12CA1 | |
| SCHEMBL11269384 | 0.85 | PTGS2 (0.46) | PTGS1PTGS2LMNATSHRCA12 | |
| SCHEMBL11271773 | 0.85 | PTGS2 (0.46) | PTGS1PTGS2LMNATSHRCA12 | |
| SCHEMBL11260940 | 0.84 | PTGS2 (0.49) | PTGS1PTGS2LMNACA12CA1 | |
| SCHEMBL11258070 | 0.83 | PTGS2 (0.45) | PTGS1PTGS2LMNACA12CA1 | |
| SCHEMBL11405698 | 0.83 | PTGS2 (0.42) | PTGS1PTGS2LMNACA12CA1 | |
| SCHEMBL11266172 | 0.83 | PTGS2 (0.52) | PTGS1PTGS2LMNACA12CA1 | |
| SCHEMBL11271132 | 0.82 | PTGS2 (0.48) | PTGS1PTGS2LMNACA12CA1 | |
| SCHEMBL11162495 | 0.82 | PTGS2 (0.47) | PTGS1PTGS2LMNACA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4362738-A | ANTIINFLAMMATORIES | DR. KARL THOMAE GMBH (DE) | 1982-12-07 | — | — | US | disclosed |