Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 3/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.35 |
| ▸ | MIF | P14174 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11051998 | 0.99 | ESR1 (0.39) | ESR1ESR2MAOBMAOAMAPT | |
| SCHEMBL11049014 | 0.84 | MAOB (0.49) | MAOBMAOAALDH1A1TSHR | |
| SCHEMBL19746 | 0.83 | CYP19A1 (0.45) | MAOBMAOAMAPTGAAALDH1A1 | |
| SCHEMBL11733122 | 0.82 | CYP19A1 (0.44) | MAOBMAOAMAPTGAAALDH1A1 | |
| Methane SCHEMBL27973705 | 0.82 | CYP19A1 (0.44) | MAOBMAOAMAPTGAAALDH1A1 | |
| SCHEMBL2283832 | 0.81 | CYP3A4 (0.49) | ESR1ESR2MAOBMAOAMAPT | |
| Methoxymethane SCHEMBL27610365 | 0.81 | KDM4E (0.42) | MAOBMAOAMAPTGAAALDH1A1 | |
| SCHEMBL2474551 | 0.81 | MAOB (0.49) | MAOBMAOAKDM4E | |
| SCHEMBL10381296 | 0.81 | POLB (0.42) | MAOBMAOAMAPTGAAALDH1A1 | |
| SCHEMBL127705 | 0.80 | MAPT (0.52) | MAOBMAOAMAPTTP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0025161-B1 | 3-METHYLENE FLAVANONES AND 3-METHYLENE CHROMANONES, ANTIMICROBIAL COMPOSITION CONTAINING SAME AND METHOD OF INHIBITING THE GROWTH OF MICROORGANISMS | MILES LABORATORIES, INC. (US) | 1982-06-09 | — | — | EP | disclosed |
| EP-0025161-A1 | 3-Methylene flavanones and 3-methylene chromanones, antimicrobial composition containing same and method of inhibiting the growth of microorganisms | MILES LABORATORIES, INC. (US) | 1981-03-18 | — | — | EP | disclosed |
| US-4241069-A | MICROBIOCIDES | MILES LABORATORIES, INC. (US) | 1980-12-23 | — | — | US | disclosed |