SCHEMBL127705

SCHEMBL127705

COc1ccc(C2Oc3ccccc3CC2=O)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.52
MAOB P27338 4/20 0.52
NPC1 O15118 2/20 0.52
RAB9A P51151 2/20 0.52
GABRA1 P14867 2/20 0.50
GABRB2 P47870 2/20 0.50
LMNA P02545 2/20 0.47
NPSR1 Q6W5P4 1/20 0.46
CYP19A1 P11511 3/20 0.46
F10 P00742 1/20 0.43
CYP3A4 P08684 1/20 0.43
ABCB1 P08183 1/20 0.42
AR P10275 1/20 0.42
ABCG2 Q9UNQ0 1/20 0.42
HPGD P15428 2/20 0.42
TP53 P04637 1/20 0.42
MAOA P21397 1/20 0.42
PTGS2 P35354 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
TSHR P16473 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11252782 0.85 LMNA (0.53) MAPTMAOBNPC1RAB9ALMNA
SCHEMBL11049014 0.84 MAOB (0.49) MAOBLMNACYP19A1F10MAOA
SCHEMBL131516 0.83 CYP19A1 (0.52) MAPTMAOBLMNANPSR1CYP19A1
SCHEMBL126193 0.83 ABCG2 (0.55) MAPTMAOBNPC1RAB9AGABRA1
SCHEMBL19746 0.83 CYP19A1 (0.45) MAPTMAOBRAB9ACYP19A1AR
SCHEMBL5505269 0.82 GABRA1 (0.37) MAPTMAOBNPC1RAB9AGABRA1
SCHEMBL11733122 0.82 CYP19A1 (0.44) MAPTMAOBRAB9ACYP19A1AR
SCHEMBL7195895 0.81 ALDH1A1 (0.50) MAPTMAOBGABRA1GABRB2LMNA
SCHEMBL11242838 0.81 LMNA (0.46) MAPTMAOBNPC1RAB9AGABRA1
SCHEMBL2283832 0.81 CYP3A4 (0.49) MAPTMAOBNPC1RAB9ACYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 326 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025091065-A1 FLAVONOID COMPOSITION GRETALS AUSTRALIA PTY LTD (AU) 2025-05-08 WO claimed
US-20230172901-A1 COMPOSITIONS AND METHODS FOR THE PROPHYLAXIS AND TREATMENT OF FIBROTIC AND INFLAMMATORY CONDITIONS GRETALS AUSTRALIA PTY LTD (AU) 2023-06-08 US claimed
EP-4146194-A1 COMPOSITIONS AND METHODS FOR THE PROPHYLAXIS AND TREATMENT OF FIBROTIC AND INFLAMMATORY CONDITIONS Gretals Australia Pty Ltd (AU) 2023-03-15 EP claimed
WO-2021222987-A1 COMPOSITIONS AND METHODS FOR THE PROPHYLAXIS AND TREATMENT OF FIBROTIC AND INFLAMMATORY CONDITIONS GRETALS AUSTRALIA PTY LTD (AU) 2021-11-11 WO claimed
US-20260033492-A1 Pest Repellents and Uses Thereof SENSORYGEN INC (US) 2026-02-05 US disclosed
WO-2025091065-A1 FLAVONOID COMPOSITION GRETALS AUSTRALIA PTY LTD (AU) 2025-05-08 WO disclosed
US-12280129-B2 Compositions and methods for improved skin care PINSKY MARK A (US) 2025-04-22 US disclosed
CN-117761174-A Method for detecting metabolites in konjak and rhizosphere soil at different Pcc infection stages 昆明学院 2024-03-26 CN disclosed
EP-4307910-A1 FLAVORED FIBER BLENDS AND THEIR COMESTIBLE USE Firmenich SA (CH) 2024-01-24 EP disclosed
US-20230292754-A1 Pest Repellents and Uses Thereof UNIVERSITY OF CALIFORNIA RIVERSIDE 2023-09-21 US disclosed
EP-4228408-A1 PEST REPELLENTS AND USES THEREOF Sensorygen, Inc. (US) 2023-08-23 EP disclosed
US-20230172901-A1 COMPOSITIONS AND METHODS FOR THE PROPHYLAXIS AND TREATMENT OF FIBROTIC AND INFLAMMATORY CONDITIONS GRETALS AUSTRALIA PTY LTD (AU) 2023-06-08 US disclosed
US-6093411-A AN EMULSION COMPRISING FLAVONOIDS FOR PREVENTING OR TREATING SKIN DISORDERS THE PROCTER & GAMBLE COMPANY (US) 2000-07-25 US disclosed
US-6051602-A METHODS FOR PREVENTION OR TREATING SKIN DISORDERS USING FLAVONOID COMPOUNDS THE PROCTER & GAMBLE COMPANY (US) 2000-04-18 US disclosed
WO-1999047118-A1 COMPOSITIONS FOR REGULATING SKIN APPEARANCE THE PROCTER & GAMBLE COMPANY (US) 1999-09-23 WO disclosed
WO-1999047113-A1 COMPOSITIONS FOR REGULATING SKIN APPEARANCE THE PROCTER & GAMBLE COMPANY (US) 1999-09-23 WO disclosed
WO-1999047119-A1 METHODS FOR REGULATING SKIN APPEARANCE THE PROCTER & GAMBLE COMPANY (US) 1999-09-23 WO disclosed
EP-0025161-B1 3-METHYLENE FLAVANONES AND 3-METHYLENE CHROMANONES, ANTIMICROBIAL COMPOSITION CONTAINING SAME AND METHOD OF INHIBITING THE GROWTH OF MICROORGANISMS MILES LABORATORIES, INC. (US) 1982-06-09 EP disclosed
EP-0025161-A1 3-Methylene flavanones and 3-methylene chromanones, antimicrobial composition containing same and method of inhibiting the growth of microorganisms MILES LABORATORIES, INC. (US) 1981-03-18 EP disclosed
US-4241069-A MICROBIOCIDES MILES LABORATORIES, INC. (US) 1980-12-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260033492-A1 Pest Repellents and Uses Thereof F3, TFPI, FLI1 MAPT 122/4885MAOB 1790/4885NPC1 1031/4885
US-20230172901-A1 COMPOSITIONS AND METHODS FOR THE PROPHYLAXIS AND TREATMENT OF FIBROTIC AND INFLAMMATORY CONDITIONS MMP1, COL1A1, SERPINB1 MAPT 3241/4885MAOB 2184/4885NPC1 1063/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.