Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.43 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PPIA | P62937 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3691542 | 0.83 | CYP2C9 (0.44) | MEN1KMT2ALMNARAB9AMAPT | |
| SCHEMBL2014692 | 0.81 | KEAP1 (0.44) | MEN1KMT2AKEAP1LMNARAB9A | |
| SCHEMBL6852217 | 0.81 | KMT2A (0.81) | MEN1KMT2APIN1LMNARAB9A | |
| SCHEMBL31053816 | 0.80 | FFAR1 (0.49) | MEN1KMT2AHTR2AHTR2CHTR2B | |
| SCHEMBL18338986 | 0.80 | FFAR1 (0.49) | MEN1KMT2AHTR2AHTR2CHTR2B | |
| SCHEMBL838634 | 0.78 | KCNQ3 (0.56) | MEN1KMT2ALMNARAB9AMAPT | |
| SCHEMBL12354198 | 0.78 | KCNQ3 (0.56) | MEN1KMT2ALMNARAB9AMAPT | |
| SCHEMBL22492062 | 0.78 | KCNQ3 (0.56) | MEN1KMT2ALMNARAB9AMAPT | |
| SCHEMBL22492058 | 0.78 | KCNQ3 (0.56) | MEN1KMT2ALMNARAB9AMAPT | |
| SCHEMBL1752183 | 0.77 | SLC6A2 (0.56) | MEN1KMT2ALMNARAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4336398-A | Process for the preparation of basic esters of substituted hydroxycyclohexanecarboxylic acids | LABORATORIO GUIDOTTI & C. S.P.A. (IT) | 1982-06-22 | — | — | US | disclosed |