SCHEMBL112597

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL114002	0.92	CXCR3 (0.57)	CXCR3KCNH2ALDH1A1SMN1; SMN2TSHR
	SCHEMBL112666	0.91	CXCR3 (0.56)	CXCR3KCNH2ALDH1A1SMN1; SMN2TSHR
	SCHEMBL113704	0.91	CXCR3 (0.56)	CXCR3KCNH2ALDH1A1SMN1; SMN2TSHR
	SCHEMBL110415	0.89	CXCR3 (0.58)	CXCR3KCNH2ALDH1A1SMN1; SMN2TSHR
	SCHEMBL111889	0.89	CXCR3 (0.67)	CXCR3KCNH2ALDH1A1SMN1; SMN2TSHR
	SCHEMBL111833	0.88	CXCR3 (0.61)	CXCR3KCNH2ALDH1A1SMN1; SMN2TSHR
	SCHEMBL111164	0.86	CXCR3 (0.59)	CXCR3KCNH2ALDH1A1SMN1; SMN2TSHR
	SCHEMBL111619	0.86	CXCR3 (0.58)	CXCR3KCNH2ALDH1A1SMN1; SMN2TSHR
	SCHEMBL112255	0.85	CXCR3 (0.55)	CXCR3KCNH2SMN1; SMN2TSHRHSD17B10
	SCHEMBL109673	0.85	CXCR3 (0.55)	CXCR3KCNH2ALDH1A1SMN1; SMN2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.