Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11261948 | 0.88 | EPHX1 (0.35) | ALDH1A1GAATSHRCYP2D6CYP2C19 | |
| SCHEMBL11074989 | 0.88 | EPHX1 (0.35) | ALDH1A1GAATSHRCYP2D6CYP2C19 | |
| SCHEMBL11266643 | 0.83 | ALDH1A1 (0.32) | ALDH1A1CYP2D6CYP2C19MEN1KMT2A | |
| SCHEMBL11073548 | 0.83 | EPHX1 (0.41) | ALDH1A1EPHX1 | |
| SCHEMBL11255902 | 0.83 | EPHX1 (0.41) | ALDH1A1EPHX1 | |
| SCHEMBL11262635 | 0.83 | EPHX1 (0.39) | ALDH1A1EPHX1HSD11B1 | |
| SCHEMBL11262630 | 0.83 | EPHX1 (0.39) | ALDH1A1EPHX1HSD11B1 | |
| SCHEMBL11251126 | 0.81 | HRH3 (0.38) | — | |
| SCHEMBL11079656 | 0.78 | EPHX1 (0.35) | ALDH1A1GAATSHREPHX1DRD2 | |
| SCHEMBL11265228 | 0.74 | CYP2D6 (0.41) | CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4335138-A | HYPNOTIC, SEDATIVE | BASF AKTIENGESELLSCHAFT (DE) | 1982-06-15 | — | — | US | disclosed |