Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 3/20 | 0.53 |
| ▸ | HTR1D | P28221 | 2/20 | 0.53 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.53 |
| ▸ | HTR3B | O95264 | 1/20 | 0.53 |
| ▸ | HTR1A | P08908 | 1/20 | 0.53 |
| ▸ | HTR1B | P28222 | 1/20 | 0.53 |
| ▸ | HTR2A | P28223 | 1/20 | 0.53 |
| ▸ | HTR1E | P28566 | 1/20 | 0.53 |
| ▸ | HTR1F | P30939 | 1/20 | 0.53 |
| ▸ | HTR7 | P34969 | 1/20 | 0.53 |
| ▸ | HTR2B | P41595 | 1/20 | 0.53 |
| ▸ | HTR3A | P46098 | 1/20 | 0.53 |
| ▸ | HTR5A | P47898 | 1/20 | 0.53 |
| ▸ | HTR6 | P50406 | 1/20 | 0.53 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.53 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.53 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16372578 | 0.79 | CYP3A4 (0.49) | MAPTKDM4EALDH1A1MEN1POLB | |
| SCHEMBL27499616 | 0.76 | MEN1 (0.42) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL13754293 | 0.75 | MAPT (0.48) | MAPTKDM4EALDH1A1MEN1POLB | |
| SCHEMBL6967405 | 0.73 | MEN1 (0.40) | MAPTALDH1A1MEN1POLBKMT2A | |
| SCHEMBL25519810 | 0.71 | TAAR1 (0.61) | HTR2CHTR2AHTR2BMAPTTAAR1 | |
| SCHEMBL30101707 | 0.71 | TAAR1 (0.61) | HTR2CHTR2AHTR2BMAPTTAAR1 | |
| SCHEMBL5460784 | 0.71 | MEN1 (0.44) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL21591954 | 0.71 | MAPT (0.44) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL546296 | 0.71 | MAPT (0.56) | HTR3EHTR3BHTR1AHTR3AHTR3D | |
| SCHEMBL29415600 | 0.71 | MAPT (0.56) | HTR3EHTR3BHTR1AHTR3AHTR3D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4333930-A | TREATMENT OF CENTRAL NERVOUS DISORDERS, ANALGESICS, ANTIDEPRESSANTS | LABORATOIRES SARGET (FR) | 1982-06-08 | — | — | US | disclosed |