Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 6/20 | 0.56 |
| ▸ | PTGFR | P43088 | 6/20 | 0.56 |
| ▸ | PTGER3 | P43115 | 4/20 | 0.56 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | SLCO2A1 | Q92959 | 2/20 | 0.49 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.49 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.46 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11161148 | 1.00 | TBXA2R (0.56) | TBXA2RPTGFRPTGER3PTGER1LMNA | |
| SCHEMBL9483584 | 0.93 | ALDH1A1 (0.51) | TBXA2RPTGFRPTGER3PTGER1LMNA | |
| SCHEMBL10626177 | 0.93 | ALDH1A1 (0.51) | TBXA2RPTGFRPTGER3PTGER1LMNA | |
| SCHEMBL9483578 | 0.93 | ALDH1A1 (0.51) | TBXA2RPTGFRPTGER3PTGER1LMNA | |
| SCHEMBL10626179 | 0.93 | ALDH1A1 (0.51) | TBXA2RPTGFRPTGER3PTGER1LMNA | |
| SCHEMBL9482108 | 0.92 | TBXA2R (0.47) | TBXA2RPTGFRPTGER3PTGER1LMNA | |
| SCHEMBL9482104 | 0.92 | TBXA2R (0.47) | TBXA2RPTGFRPTGER3PTGER1LMNA | |
| SCHEMBL11733787 | 0.90 | TBXA2R (0.57) | TBXA2RPTGFRPTGER3PTGER1LMNA | |
| SCHEMBL10835463 | 0.90 | PDE4D (0.46) | TBXA2RPTGFRPTGER3PTGER1LMNA | |
| SCHEMBL10657235 | 0.90 | PDE4D (0.46) | TBXA2RPTGFRPTGER3PTGER1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4338316-A | PROSTAGLANDIN F SERIES ANALOGUES | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1982-07-06 | — | — | US | disclosed |
| EP-0010360-B1 | PROSTANE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR PHARMACEUTICAL COMPOSITIONS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-06-02 | — | — | EP | disclosed |